Bimal N. Desai, Ph.D.
Affiliations: | Harvard University, Cambridge, MA, United States |
Area:
Chemical biologyGoogle:
"Bimal Desai"Parents
Sign in to add mentor| Stuart L. Schreiber | grad student | 2002 | Harvard | |
| (Mitochondria-associated FRAP: Coordinating the growth -regulatory signals with mitochondrial activity.) | ||||
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Publications
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| Gupta S, Chiu YH, Manjegowda MC, et al. (2024) Distinct properties and activation of hexameric and heptameric Pannexin 1 channel concatemers. The Journal of General Physiology. 157 |
| Chiu YH, Medina CB, Doyle CA, et al. (2021) Deacetylation as a receptor-regulated direct activation switch for pannexin channels. Nature Communications. 12: 4482 |
| DeLalio LJ, Masati E, Mendu S, et al. (2020) PANNEXIN 1 CHANNELS IN RENIN-EXPRESSING CELLS INFLUENCE RENIN SECRETION AND BLOOD PRESSURE HOMEOSTASIS. Kidney International |
| Schappe MS, Szteyn K, Stremska ME, et al. (2018) Chanzyme TRPM7 Mediates the Ca2+ Influx Essential for Lipopolysaccharide-Induced Toll-Like Receptor 4 Endocytosis and Macrophage Activation. Immunity. 48: 59-74.e5 |
| Chiu YH, Schappe MS, Desai BN, et al. (2017) Revisiting multimodal activation and channel properties of Pannexin 1. The Journal of General Physiology |
| Lam PY, Mendu SK, Mills RW, et al. (2017) A high-conductance chemo-optogenetic system based on the vertebrate channel Trpa1b. Scientific Reports. 7: 11839 |
| Good ME, Poon IK, Chiu Y, et al. (2017) Spironolactone can act on pannexin1 channels in smooth muscle cells to regulate vasoconstriction and blood pressure The Faseb Journal. 31 |
| Py BF, Jin M, Desai BN, et al. (2014) Caspase-11 controls interleukin-1β release through degradation of TRPC1. Cell Reports. 6: 1122-8 |
| Desai BN, Krapivinsky G, Navarro B, et al. (2012) Cleavage of TRPM7 releases the kinase domain from the ion channel and regulates its participation in Fas-induced apoptosis. Developmental Cell. 22: 1149-62 |
| Jin J, Desai BN, Navarro B, et al. (2008) Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science (New York, N.Y.). 322: 756-60 |