John Sanders, Ph.D.
Affiliations: | 2005 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
biomolecular NMRGoogle:
"John Sanders"Parents
Sign in to add mentor| Eric Oldfield | grad student | 2005 | UIUC | |
| (An improved understanding of bisphosphonates through computational techniques.) | ||||
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Publications
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| Burlein C, Wang C, Min X, et al. (2017) Discovery of a Distinct Chemical and Mechanistic Class of Allosteric HIV-1 Integrase Inhibitors with Antiretroviral Activity. Acs Chemical Biology |
| Mao J, Mukherjee S, Zhang Y, et al. (2006) Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. Journal of the American Chemical Society. 128: 14485-97 |
| Benaim G, Sanders JM, Garcia-Marchán Y, et al. (2006) Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole. Journal of Medicinal Chemistry. 49: 892-9 |
| Sanders JM, Song Y, Chan JM, et al. (2005) Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption. Journal of Medicinal Chemistry. 48: 2957-63 |
| Song Y, Zhang Y, Wang H, et al. (2004) Synthesis of chiral phosphoantigens and their activity in gamma delta T cell stimulation. Bioorganic & Medicinal Chemistry Letters. 14: 4471-7 |
| Yajima S, Hara K, Sanders JM, et al. (2004) Crystallographic structures of two bisphosphonate:1-deoxyxylulose-5-phosphate reductoisomerase complexes. Journal of the American Chemical Society. 126: 10824-5 |
| Sanders JM, Ghosh S, Chan JM, et al. (2004) Quantitative structure-activity relationships for gammadelta T cell activation by bisphosphonates. Journal of Medicinal Chemistry. 47: 375-84 |
| Sanders JM, Gómez AO, Mao J, et al. (2003) 3-D QSAR investigations of the inhibition of Leishmania major farnesyl pyrophosphate synthase by bisphosphonates. Journal of Medicinal Chemistry. 46: 5171-83 |
| Montalvetti A, Fernandez A, Sanders JM, et al. (2003) Farnesyl pyrophosphate synthase is an essential enzyme in Trypanosoma brucei. In vitro RNA interference and in vivo inhibition studies. The Journal of Biological Chemistry. 278: 17075-83 |
| Martin MB, Sanders JM, Kendrick H, et al. (2002) Activity of bisphosphonates against Trypanosoma brucei rhodesiense. Journal of Medicinal Chemistry. 45: 2904-14 |