Andrew N. Lowell, Ph.D.

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
asymmetric catalysts
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"Andrew Lowell"

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Marisa C. Kozlowski grad student 2008 Penn
 (Toward the total synthesis of purpuromycin: A hemiketal conjugate addition strategy and use of a diketone to aid spiroketal formation.)
Yoko Yamakoshi post-doc Penn
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Publications

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Fracassi A, Qiao H, Lowell AN, et al. (2025) Natural and Synthetic LDL-Based Imaging Probes for the Detection of Atherosclerotic Plaques. Acs Pharmacology & Translational Science. 8: 578-591
Sherman DH, Koch AA, Schmidt J, et al. (2020) Probing Selectivity and Creating Structural Diversity Through Hybrid Polyketide Synthases. Angewandte Chemie (International Ed. in English)
Khatri Y, Hohlman RM, Mendoza J, et al. (2020) Multi-component microscale biosynthesis of unnatural cyanobacterial indole alkaloids. Acs Synthetic Biology
Li S, Newmister SA, Lowell AN, et al. (2020) Control of stereoselectivity in diverse hapalindole metabolites is mediated by cofactor induced combinatorial pairing of Stig cyclases. Angewandte Chemie (International Ed. in English)
Aroua S, Lowell AN, Ray A, et al. (2018) Larger Substituents on Amide Cavitands Induce Bigger Cavities. Organic Letters
Skiba MA, Sikkema AP, Moss NA, et al. (2018) Biosynthesis of t-Butyl in Apratoxin A: Functional Analysis and Architecture of a PKS Loading Module. Acs Chemical Biology
Newmister SA, Li S, Garcia-Borràs M, et al. (2018) Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis. Nature Chemical Biology
Lowell AN, DeMars MD, Slocum ST, et al. (2017) Chemoenzymatic total synthesis and structural diversification of tylactone-based macrolide antibiotics through late-stage polyketide assembly, tailoring, and C-H functionalization. Journal of the American Chemical Society
DeMars MD, Sheng F, Park SR, et al. (2016) Biochemical and Structural Characterization of MycCI, a Versatile P450 Biocatalyst from the Mycinamicin Biosynthetic Pathway. Acs Chemical Biology
Li S, Lowell AN, Yu F, et al. (2015) Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C-C Bond-Forming Cascade. Journal of the American Chemical Society
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