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David D. Ford, Ph.D.

Affiliations: 
2013 Chemistry Harvard University, Cambridge, MA, United States 
Area:
Mechanistic and synthetic chemistry
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Eric N. Jacobsen grad student 2013 Harvard
 (The Role of Catalyst-Catalyst Interactions in Asymmetric Catalysis with (salen)Cobalt(III) Complexes and Hydrogen-Bond Donors.)

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Publications

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Akin A, Barrila MT, Brandt TA, et al. (2017) A Scalable Route for the Regio- and Enantioselective Preparation of a Tetrazole Prodrug: Application to the Multi-Gram-Scale Synthesis of a PCSK9 Inhibitor Organic Process Research & Development. 21: 1990-2000
Ford DD, Lehnherr D, Kennedy CR, et al. (2016) Anion-Abstraction Catalysis: The Cooperative Mechanism of α-Chloroether Activation by Dual Hydrogen-Bond Donors. Acs Catalysis. 6: 4616-4620
Kennedy CR, Lehnherr D, Rajapaksa NS, et al. (2016) Mechanism-Guided Development of a Highly Active Bis-Thiourea Catalyst for Anion-Abstraction Catalysis. Journal of the American Chemical Society. 138: 13525–8
Lehnherr D, Ford DD, Bendelsmith AJ, et al. (2016) Conformational Control of Chiral Amido-Thiourea Catalysts Enables Improved Activity and Enantioselectivity. Organic Letters. 18: 3214-7
Ford DD, Lehnherr D, Kennedy CR, et al. (2016) On- and Off-Cycle Catalyst Cooperativity in Anion-Binding Catalysis. Journal of the American Chemical Society. 138: 7860-3
Ford DD, Lehnherr D, Kennedy CR, et al. (2016) Anion-Abstraction Catalysis: The Cooperative Mechanism of α-Chloroether Activation by Dual H-Bond Donors Acs Catalysis. 6: 4616–4620
Ford DD, Nielsen LP, Zuend SJ, et al. (2013) Mechanistic basis for high stereoselectivity and broad substrate scope in the (salen)Co(III)-catalyzed hydrolytic kinetic resolution. Journal of the American Chemical Society. 135: 15595-608
Nielsen LP, Zuend SJ, Ford DD, et al. (2012) Mechanistic basis for high reactivity of (salen)Co-OTs in the hydrolytic kinetic resolution of terminal epoxides. The Journal of Organic Chemistry. 77: 2486-95
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