John S. Comninos, Ph.D.

Affiliations: 
2011 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
steroid hormones
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"John Comninos"

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John A. Katzenellenbogen grad student 2011 UIUC
 (I. Design and synthesis of estrogen receptor gene switches. II. Design and synthesis of estrogen receptor ligands occupying an auxiliary binding pocket.)
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Publications

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Zhou HB, Collins ML, Gunther JR, et al. (2007) Bicyclo[2.2.2]octanes: close structural mimics of the nuclear receptor-binding motif of steroid receptor coactivators. Bioorganic & Medicinal Chemistry Letters. 17: 4118-22
Seo JW, Comninos JS, Chi DY, et al. (2006) Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer. Journal of Medicinal Chemistry. 49: 2496-511
Zhou HB, Comninos JS, Stossi F, et al. (2005) Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure. Journal of Medicinal Chemistry. 48: 7261-74
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