John S. Comninos, Ph.D.
Affiliations: | 2011 | Chemistry | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
steroid hormonesGoogle:
"John Comninos"Parents
Sign in to add mentorJohn A. Katzenellenbogen | grad student | 2011 | UIUC | |
(I. Design and synthesis of estrogen receptor gene switches. II. Design and synthesis of estrogen receptor ligands occupying an auxiliary binding pocket.) |
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Publications
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Zhou HB, Collins ML, Gunther JR, et al. (2007) Bicyclo[2.2.2]octanes: close structural mimics of the nuclear receptor-binding motif of steroid receptor coactivators. Bioorganic & Medicinal Chemistry Letters. 17: 4118-22 |
Seo JW, Comninos JS, Chi DY, et al. (2006) Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer. Journal of Medicinal Chemistry. 49: 2496-511 |
Zhou HB, Comninos JS, Stossi F, et al. (2005) Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure. Journal of Medicinal Chemistry. 48: 7261-74 |