Denise A. Colby, Ph.D.

Affiliations: 
2008 University of California, Berkeley, Berkeley, CA, United States 
Area:
chemical synthesis
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"Denise Colby"

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Jonathan A. Ellman grad student 2008 UC Berkeley
 (Synthetic and mechanistic investigations of transformations proceeding via chelation-assisted carbon-hydrogen bond activation.)
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Publications

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Lash TD, Lammer AD, Idate AS, et al. (2012) Preparation of azulene-derived fulvenedialdehydes and their application to the synthesis of stable adj-dicarbaporphyrinoids. The Journal of Organic Chemistry. 77: 2368-81
Colby DA, Tsai AS, Bergman RG, et al. (2012) Rhodium catalyzed chelation-assisted C-H bond functionalization reactions. Accounts of Chemical Research. 45: 814-25
Han C, Kim EH, Colby DA. (2011) Cleavage of carbon-carbon bonds through the mild release of trifluoroacetate: generation of α,α-difluoroenolates for aldol reactions. Journal of the American Chemical Society. 133: 5802-5
Crimmin MR, Colby DA, Ellman JA, et al. (2011) Synthesis and coordination chemistry of tri-substituted benzamidrazones. Dalton Transactions (Cambridge, England : 2003). 40: 514-22
Colby DA, Bergman RG, Ellman JA. (2010) Rhodium-catalyzed C-C bond formation via heteroatom-directed C-H bond activation. Chemical Reviews. 110: 624-55
Ishikawa H, Colby DA, Seto S, et al. (2009) Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues. Journal of the American Chemical Society. 131: 4904-16
Colby DA, Bergman RG, Ellman JA. (2008) Synthesis of dihydropyridines and pyridines from imines and alkynes via C-H activation. Journal of the American Chemical Society. 130: 3645-51
Ishikawa H, Colby DA, Boger DL. (2008) Direct coupling of catharanthine and vindoline to provide vinblastine: total synthesis of (+)- and ent-(-)-vinblastine. Journal of the American Chemical Society. 130: 420-1
Lash TD, Colby DA, Idate AS, et al. (2007) Fulvene dialdehyde strategy for adj-dicarbaporphyrinoid synthesis: preparation of a 22-carbaazuliporphyrin. Journal of the American Chemical Society. 129: 13800-1
Lawhorn BG, Boga SB, Wolkenberg SE, et al. (2006) Total synthesis and evaluation of cytostatin, its C10-C11 diastereomers, and additional key analogues: impact on PP2A inhibition. Journal of the American Chemical Society. 128: 16720-32
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