Stephen N. Greszler, Ph.D.
Affiliations: | 2010 | Chemistry | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Synthetic Organic Chemistry, Asymmetric CatalysisGoogle:
"Stephen Greszler"Parents
Sign in to add mentor| Jeffrey S. Johnson | grad student | 2010 | UNC Chapel Hill | |
| (I. Catalytic redox-initiated glycolate aldol additions of silyl glyoxylates. II. Diastereoselective de novo synthesis of pentasubstituted gamma-butyrolactones from silyl glyoxylates and ketones via double Reformatsky reactions. III. Progress toward the to) | ||||
| Glenn Christopher Micalizio | post-doc | 2010-2012 | The Scripps Research Institute, Scripps Florida | |
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Publications
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| Marvin CC, Greszler SN, Shelat BH, et al. (2022) Synthesis of A-9758, an Inverse Agonist of Retinoic Acid-Related Orphan Receptor γt. Acs Omega. 7: 44383-44389 |
| Greszler SN, Zhao G, Shelat B, et al. (2022) Enabling Asymmetric Synthesis of ABBV-3748, a Corrector Compound for the Treatment of Cystic Fibrosis. Organic Letters |
| Buchman M, Farney EP, Greszler SN, et al. (2022) Lithioarene Cycliacylation and Pd-Catalyzed Aminoethylation/Cyclization to Access Electronically Diverse Saturated Isoquinoline Derivatives. The Journal of Organic Chemistry. 87: 776-789 |
| Voight EA, Greszler SN, Hartung J, et al. (2021) Desymmetrization of pibrentasvir for efficient prodrug synthesis. Chemical Science. 12: 10076-10082 |
| Greszler SN, Zhao G, Buchman M, et al. (2020) General Asymmetric Synthesis of Densely Functionalized Pyrrolidines via Endo-Selective [3+2] Cycloaddition of β-Quaternary-Substituted Nitroalkenes and Azomethine Ylides. The Journal of Organic Chemistry |
| Greszler SN, Halvorsen GT, Voight EA. (2017) Synthesis of Substituted Cyclopropanecarboxylates via Room Temperature Palladium-Catalyzed α-Arylation of Reformatsky Reagents. Organic Letters |
| Aquino C, Greszler SN, Micalizio GC. (2016) Synthesis of the Cortistatin Pentacyclic Core by Alkoxide-Directed Metallacycle-Mediated Annulative Cross-Coupling. Organic Letters |
| Boyce GR, Greszler SN, Johnson JS, et al. (2012) Silyl glyoxylates. Conception and realization of flexible conjunctive reagents for multicomponent coupling. The Journal of Organic Chemistry. 77: 4503-15 |
| Greszler SN, Reichard HA, Micalizio GC. (2012) Asymmetric synthesis of dihydroindanes by convergent alkoxide-directed metallacycle-mediated bond formation. Journal of the American Chemical Society. 134: 2766-74 |
| Greszler SN, Malinowski JT, Johnson JS. (2011) Formal synthesis of leustroducsin B via Reformatsky/Claisen condensation of silyl glyoxylates. Organic Letters. 13: 3206-9 |