Denise M. Kenski, Ph.D.
Affiliations: | 2005 | University of California, San Francisco, San Francisco, CA |
Area:
signal transduction pathways in cells and whole organismsGoogle:
"Denise Kenski"Parents
Sign in to add mentor| Kevan Michael Shokat | grad student | 1999-2005 | UCSF | |
| (Enhancing specificity of analog-sensitive kinases: The role of GRKs in membrane trafficking of the mu-opioid receptor.) | ||||
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Publications
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| Kenski DM, Willingham AT, Haringsma HJ, et al. (2012) In vivo activity and duration of short interfering RNAs containing a synthetic 5'-phosphate. Nucleic Acid Therapeutics. 22: 90-5 |
| Haringsma HJ, Li JJ, Soriano F, et al. (2012) mRNA knockdown by single strand RNA is improved by chemical modifications. Nucleic Acids Research. 40: 4125-36 |
| Butora G, Kenski DM, Cooper AJ, et al. (2011) Nucleoside optimization for RNAi: a high-throughput platform. Journal of the American Chemical Society. 133: 16766-9 |
| Kenski DM, Cooper AJ, Li JJ, et al. (2010) Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo. Nucleic Acids Research. 38: 660-71 |
| Jaiswal BS, Janakiraman V, Kljavin NM, et al. (2009) Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. Cancer Cell. 16: 463-74 |
| Murriel CL, Chen H, Kenski D, et al. (2009) Abstract LB-189: BRAFdeletion and pharmacological inhibition enhance K-ras driven tumorigenesis Cancer Research. 70 |
| Kung C, Kenski DM, Krukenberg K, et al. (2006) Selective kinase inhibition by exploiting differential pathway sensitivity. Chemistry & Biology. 13: 399-407 |
| Kenski DM, Zhang C, von Zastrow M, et al. (2005) Chemical genetic engineering of G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 280: 35051-61 |
| Zhang C, Kenski DM, Paulson JL, et al. (2005) A second-site suppressor strategy for chemical genetic analysis of diverse protein kinases. Nature Methods. 2: 435-41 |
| Kung C, Kenski DM, Dickerson SH, et al. (2005) Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 102: 3587-92 |