Cynthia L. Kinsland, Ph.D.

Affiliations: 
2000 Cornell University, Ithaca, NY, United States 
Area:
Barton Professor of Chemistry
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"Cynthia Kinsland"

Parents

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Tadhg P. Begley grad student 2000 Cornell
 (Studies on the biosynthesis of thiamin and coenzyme A.)
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Publications

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Knaus T, Eger E, Koop J, et al. (2012) Reverse structural genomics: an unusual flavin-binding site in a putative protease from Bacteroides thetaiotaomicron. The Journal of Biological Chemistry. 287: 27490-8
Lai RY, Huang S, Fenwick MK, et al. (2012) Thiamin pyrimidine biosynthesis in Candida albicans : a remarkable reaction between histidine and pyridoxal phosphate. Journal of the American Chemical Society. 134: 9157-9
Soriano EV, McCloskey DE, Kinsland C, et al. (2008) Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii. Acta Crystallographica. Section D, Biological Crystallography. 64: 377-82
McCulloch KM, Kinsland C, Begley TP, et al. (2008) Structural studies of thiamin monophosphate kinase in complex with substrates and products. Biochemistry. 47: 3810-21
Mukherjee T, Kinsland C, Begley TP. (2007) PLP catabolism: identification of the 4-pyridoxic acid dehydrogenase gene in Mesorhizobium loti MAFF303099. Bioorganic Chemistry. 35: 458-64
Burns KE, Xiang Y, Kinsland CL, et al. (2005) Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway. Journal of the American Chemical Society. 127: 3682-3
Toms AV, Kinsland C, McCloskey DE, et al. (2004) Evolutionary links as revealed by the structure of Thermotoga maritima S-adenosylmethionine decarboxylase. The Journal of Biological Chemistry. 279: 33837-46
Melnick J, Lis E, Park JH, et al. (2004) Identification of the two missing bacterial genes involved in thiamine salvage: thiamine pyrophosphokinase and thiamine kinase. Journal of Bacteriology. 186: 3660-2
Park JH, Burns K, Kinsland C, et al. (2004) Characterization of two kinases involved in thiamine pyrophosphate and pyridoxal phosphate biosynthesis in Bacillus subtilis: 4-amino-5-hydroxymethyl-2methylpyrimidine kinase and pyridoxal kinase. Journal of Bacteriology. 186: 1571-3
Melnick JS, Sprinz KI, Reddick JJ, et al. (2003) An efficient enzymatic synthesis of thiamin pyrophosphate. Bioorganic & Medicinal Chemistry Letters. 13: 4139-41
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