David T. Puerta, Ph.D.
Affiliations: | 2006 | University of California, San Diego, La Jolla, CA |
Area:
Bioinorganic and coordination chemistry. Metalloprotein inhibitors and supramolecular materialsGoogle:
"David Puerta"Parents
Sign in to add mentor| Seth M. Cohen | grad student | 2006 | UCSD | |
| (A bioinorganic approach to matrix metalloproteinase inhibition.) | ||||
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Publications
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| Thorson MK, Puerta DT, Cohen SM, et al. (2014) Inhibition of the lymphoid tyrosine phosphatase: the effect of zinc(II) ions and chelating ligand fragments on enzymatic activity. Bioorganic & Medicinal Chemistry Letters. 24: 4019-22 |
| Martin DP, Puerta DT, Cohen SM. (2014) Metalloprotein Inhibitors Ligand Design in Medicinal Inorganic Chemistry. 375-403 |
| Puerta DT, Botta M, Jocher CJ, et al. (2006) Tris(pyrone) chelates of Gd(III) as high solubility MRI-CA. Journal of the American Chemical Society. 128: 2222-3 |
| Puerta DT, Griffin MO, Lewis JA, et al. (2006) Heterocyclic zinc-binding groups for use in next-generation matrix metalloproteinase inhibitors: potency, toxicity, and reactivity. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 11: 131-8 |
| Romero-Perez D, Puerta D, Lewis J, et al. (2006) A34. Development of novel matrix metalloproteinase inhibitors and their effects on isolated stunned hearts Journal of Molecular and Cellular Cardiology. 40: 896 |
| Puerta DT, Mongan J, Tran BL, et al. (2005) Potent, selective pyrone-based inhibitors of stromelysin-1. Journal of the American Chemical Society. 127: 14148-9 |
| He H, Puerta DT, Cohen SM, et al. (2005) Structural and spectroscopic study of reactions between chelating zinc-binding groups and mimics of the matrix metalloproteinase and disintegrin metalloprotease catalytic sites: the coordination chemistry of metalloprotease inhibition. Inorganic Chemistry. 44: 7431-42 |
| Lewis JA, Tran BL, Puerta DT, et al. (2005) Synthesis, structure and spectroscopy of new thiopyrone and hydroxypyridinethione transition-metal complexes. Dalton Transactions (Cambridge, England : 2003). 2588-96 |
| Puerta DT, Cohen SM. (2004) A bioinorganic perspective on matrix metalloproteinase inhibition. Current Topics in Medicinal Chemistry. 4: 1551-73 |
| Puerta DT, Lewis JA, Cohen SM. (2004) New beginnings for matrix metalloproteinase inhibitors: identification of high-affinity zinc-binding groups. Journal of the American Chemical Society. 126: 8388-9 |