Alexander K. Showalter, Ph.D.

Affiliations: 
2002 Ohio State University, Columbus, Columbus, OH 
Area:
Protein Structure-Function, NMR, Enzyme Mechanism
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"Alexander Showalter"

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Ming-Daw Tsai grad student 2002 Ohio State
 (Kinetic studies of two error-prone DNA repair enzymes: Possible mechanisms for viral mutagenesis.)
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Publications

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Showalter AK, Lamarche BJ, Bakhtina M, et al. (2006) Mechanistic comparison of high-fidelity and error-prone DNA polymerases and ligases involved in DNA repair. Chemical Reviews. 106: 340-60
Lamarche BJ, Showalter AK, Tsai MD. (2005) An error-prone viral DNA ligase. Biochemistry. 44: 8408-17
Showalter AK, Tsai MD. (2002) A reexamination of the nucleotide incorporation fidelity of DNA polymerases. Biochemistry. 41: 10571-6
Showalter AK, Byeon IJ, Su MI, et al. (2001) Solution structure of a viral DNA polymerase X and evidence for a mutagenic function. Nature Structural Biology. 8: 942-6
Showalter AK, Tsai MD. (2001) A DNA polymerase with specificity for five base pairs. Journal of the American Chemical Society. 123: 1776-7
Arndt JW, Gong W, Zhong X, et al. (2001) Insight into the catalytic mechanism of DNA polymerase beta: structures of intermediate complexes. Biochemistry. 40: 5368-75
Kraynov VS, Showalter AK, Liu J, et al. (2000) DNA polymerase beta: contributions of template-positioning and dNTP triphosphate-binding residues to catalysis and fidelity. Biochemistry. 39: 16008-15
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