Carissa J. Wiederholt, Ph.D.
Affiliations: | 2005 | Johns Hopkins University, Baltimore, MD |
Area:
reactivity, function, structure, and uses of nucleic acidsGoogle:
"Carissa Wiederholt"Parents
Sign in to add mentor| Marc M. Greenberg | grad student | 2005 | Johns Hopkins | |
| (The repair and mutagenesis of formamidopyrimidines.) | ||||
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Publications
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| Weledji YN, Wiederholt CJ, Delaney MO, et al. (2008) DNA polymerase bypass in vitro and in E. coli of a C-nucleotide analogue of Fapy-dG. Bioorganic & Medicinal Chemistry. 16: 4029-34 |
| Patro JN, Wiederholt CJ, Jiang YL, et al. (2007) Studies on the replication of the ring opened formamidopyrimidine, Fapy.dG in Escherichia coli. Biochemistry. 46: 10202-12 |
| Wiederholt CJ, Patro JN, Jiang YL, et al. (2005) Excision of formamidopyrimidine lesions by endonucleases III and VIII is not a major DNA repair pathway in Escherichia coli. Nucleic Acids Research. 33: 3331-8 |
| Jiang YL, Wiederholt CJ, Patro JN, et al. (2005) Synthesis of oligonucleotides containing Fapy.dG (N(6)-(2-deoxy-alpha,beta-D-erythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine) using a 5'-dimethoxytrityl dinucleotide phosphoramidite. The Journal of Organic Chemistry. 70: 141-9 |
| Wiederholt CJ, Delaney MO, Pope MA, et al. (2003) Repair of DNA containing Fapy·dG and its β-C-nucleoside analogue by formamidopyrimidine DNA glycosylase and MutY Biochemistry. 42: 9755-9760 |
| Wiederholt CJ, Delaney MO, Greenberg MM. (2002) Interaction of DNA containing Fapy.dA or its C-nucleoside analogues with base excision repair enzymes. Implications for mutagenesis and enzyme inhibition. Biochemistry. 41: 15838-44 |
| Delaney MO, Wiederholt CJ, Greenberg MM. (2002) Fapy.dA induces nucleotide misincorporation translesionally by a DNA polymerase. Angewandte Chemie (International Ed. in English). 41: 771-3 |
| Wiederholt CJ, Greenberg MM. (2002) Fapy.dG instructs Klenow exo(-) to misincorporate deoxyadenosine. Journal of the American Chemical Society. 124: 7278-9 |
| Haraguchi K, Delaney MO, Wiederholt CJ, et al. (2002) Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues. Journal of the American Chemical Society. 124: 3263-9 |
| Haraguchi K, Delaney MO, Wiederholt CJ, et al. (2001) Synthesis and characterization of oligonucleotides containing formamidopyrimidine lesions (Fapy.dA, Fapy.dG) at defined sites. Nucleic Acids Research. Supplement (2001). 129-30 |