Timothy A. Wencewicz, Ph.D.
Affiliations: | 2011 | University of Notre Dame, Notre Dame, IN, United States | |
| 2013- | Chemistry | Washington University, Saint Louis, St. Louis, MO |
Area:
chemical and enzymatic synthesis and study of biologically important, heteroatom-containing systems including amino acids, peptides, antibiotics, siderophores, and othersWebsite:
https://artsci.wustl.edu/faculty-staff/timothy-wencewiczGoogle:
"Timothy A. Wencewicz"Parents
Sign in to add mentor| Marvin J. Miller | grad student | 2011 | Notre Dame | |
| (Development of microbe-selective antibacterial agents: From small molecules to siderophores.) | ||||
| Christopher T. Walsh | post-doc | 2011-2013 | Harvard Medical School | |
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Publications
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| Ahmed SF, Balutowski A, Yang J, et al. (2024) Expanding the Substrate Selectivity of the Fimsbactin Biosynthetic Adenylation Domain, FbsH. Acs Chemical Biology |
| Ahmed SF, Balutowski A, Yang J, et al. (2024) Expanding the substrate selectivity of the fimsbactin biosynthetic adenylation domain, FbsH. Biorxiv : the Preprint Server For Biology |
| Yang J, Banas VS, Rivera GSM, et al. (2023) Siderophore Synthetase DesD Catalyzes N-to-C Condensation in Desferrioxamine Biosynthesis. Acs Chemical Biology |
| Yang J, Wencewicz TA. (2022) Reconstitution of Fimsbactin Biosynthesis from . Acs Chemical Biology |
| Yang J, Banas VS, Patel KD, et al. (2022) An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD. The Journal of Biological Chemistry. 102166 |
| Yang J, Qi Y, Blodgett JAV, et al. (2022) Multifunctional P450 Monooxygenase CftA Diversifies the Clifednamide Pool through Tandem C-H Bond Activations. Journal of Natural Products. 85: 47-55 |
| Bohac TJ, Fang L, Banas VS, et al. (2021) Synthetic Mimics of Native Siderophores Disrupt Iron Trafficking in . Acs Infectious Diseases |
| Endicott NP, Rivera GSM, Yang J, et al. (2020) Emergence of Ferrichelatase Activity in a Siderophore-Binding Protein Supports an Iron Shuttle in Bacteria. Acs Central Science. 6: 493-506 |
| Wencewicz TA. (2019) Crossroads of Antibiotic Resistance and Biosynthesis. Journal of Molecular Biology |
| Markley JL, Fang L, Gasparrini AJ, et al. (2019) Semisynthetic Analogues of Anhydrotetracycline as Inhibitors of Tetracycline Destructase Enzymes. Acs Infectious Diseases |