Sandra M. Lynch, Ph.D.

Affiliations: 
2005 Rensselaer Polytechnic Institute, Troy, NY, United States 
Area:
Protein Folding/Misfolding
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"Sandra Lynch"

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Wilfredo Colon grad student 2005 RPI
 (Kinetic folding studies of copper/zinc superoxide dismutase and mutants thereof implicated in familial amyotrophic lateral sclerosis.)
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Publications

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Lynch SM, Colón W. (2006) Dominant role of copper in the kinetic stability of Cu/Zn superoxide dismutase. Biochemical and Biophysical Research Communications. 340: 457-61
Lynch SM, Boswell SA, Colón W. (2004) Kinetic stability of Cu/Zn superoxide dismutase is dependent on its metal ligands: implications for ALS. Biochemistry. 43: 16525-31
Lynch SM, Frei B, Morrow JD, et al. (1997) Vascular superoxide dismutase deficiency impairs endothelial vasodilator function through direct inactivation of nitric oxide and increased lipid peroxidation. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2975-81
Lynch SM, Frei B. (1995) Reduction of copper, but not iron, by human low density lipoprotein (LDL). Implications for metal ion-dependent oxidative modification of LDL. The Journal of Biological Chemistry. 270: 5158-63
Lynch SM, Klevay LM. (1994) Contrasting effects of a dietary copper deficiency in male and female mice. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 205: 190-6
Lynch SM, Klevay LM. (1993) Effect of a dietary copper deficiency on plasma fibrinolytic activity in male and female mice Nutrition Research. 13: 913-922
Lynch SM, Klevay LM. (1992) Effects of a dietary copper deficiency on plasma coagulation factor activities in male and female mice The Journal of Nutritional Biochemistry. 3: 387-391
Strain JJ, Lynch SM. (1990) Excess dietary methionine decreases indices of copper status in the rat. Annals of Nutrition & Metabolism. 34: 93-7
Lynch SM, Strain JJ. (1990) Effects of skimmed milk powder, whey or casein on tissue trace element status and antioxidant enzyme activities in rats fed control and copper-deficient diets Nutrition Research. 10: 449-460
Lynch SM, Strain JJ. (1989) Dietary saturated or polyunsaturated fat and copper deficiency in the rat. Biological Trace Element Research. 22: 131-9
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