Chaim A. Schramm, Ph.D.
Affiliations: | 2012 | Biochemistry and Molecular Biophysics | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Organic Chemistry, Chemical Biology, De Novo Protein DesignGoogle:
"Chaim Schramm"Parents
Sign in to add mentor| William F. DeGrado | grad student | 2012 | Penn | |
| (Using structural bioinformatics to understand and design protein structures and interactions.) | ||||
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Publications
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| Gorman J, Du R, Lai YT, et al. (2025) Isolation and structure of broad SIV-neutralizing antibodies reveal a proximal helical MPER epitope recognized by a rhesus multi-donor class. Cell Reports. 44: 115163 |
| Morris DJ, Gorman J, Zhou T, et al. (2024) Transient glycan-shield reduction induces CD4-binding site broadly neutralizing antibodies in SHIV-infected macaques. Biorxiv : the Preprint Server For Biology |
| Wang H, Cheng C, Dal Santo JL, et al. (2024) Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques. Cell |
| Sutton MS, Pletnev S, Callahan V, et al. (2023) Vaccine elicitation and structural basis for antibody protection against alphaviruses. Cell. 186: 2672-2689.e25 |
| Welles HC, King HAD, Nettey L, et al. (2022) Broad coverage of neutralization-resistant SIV strains by second-generation SIV-specific antibodies targeting the region involved in binding CD4. Plos Pathogens. 18: e1010574 |
| Roark RS, Li H, Williams WB, et al. (2020) Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science (New York, N.Y.) |
| Wu NC, Andrews SF, Raab JE, et al. (2020) Convergent Evolution in Breadth of Two V6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host & Microbe |
| Rantalainen K, Berndsen ZT, Antanasijevic A, et al. (2020) HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies. Cell Reports. 31: 107583 |
| Olson BJ, Moghimi P, Schramm CA, et al. (2019) sumrep: A Summary Statistic Framework for Immune Receptor Repertoire Comparison and Model Validation. Frontiers in Immunology. 10: 2533 |
| Gorman J, Mason RD, Nettey L, et al. (2019) Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields. Immunity |