Jana Sefcikova, Ph.D.

Affiliations: 
2006 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
structure-function relationships in non-coding (nc)RNAs using single molecule tools and then utilize them for biomedical, bioanalytical and nanotechnological applications
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"Jana Sefcikova"

Parents

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Nils G. Walter grad student 2006 University of Michigan
 (Conformational dynamics in folding and function of the hepatitis delta virus ribozyme.)
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Publications

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Morse M, Sefcikova J, Rouzina I, et al. (2022) Structural domains of SARS-CoV-2 nucleocapsid protein coordinate to compact long nucleic acid substrates. Nucleic Acids Research
Stern HR, Sefcikova J, Chaparro VE, et al. (2019) Mammalian DNA Polymerase Kappa Activity and Specificity. Molecules (Basel, Switzerland). 24
Sefcikova J, Roth M, Yu G, et al. (2017) Cas6 processes tight and relaxed repeat RNA via multiple mechanisms: A hypothesis. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology
Hawver LA, Tehrani M, Antczak NM, et al. (2015) Point mutations in Escherichia coli DNA pol V that confer resistance to non-cognate DNA damage also alter protein-protein interactions. Mutation Research. 780: 1-14
Pant K, Nimitpattana S, Silva MC, et al. (2013) Simultaneous Interaction of E. Coli Single Stranded DNA Binding Protein and Replicativedna Polymerase III Alpha Subunit with Single-Stranded DNA Molecules Biophysical Journal. 104: 74a
Han GW, Ko J, Farr CL, et al. (2011) Crystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activity. Proteins. 79: 2146-60
Beuning PJ, Fang J, Sefcikova J, et al. (2010) The Dynamic DNA Damage Inducible Protein UmuD Inhibits Replication Biophysical Journal. 98: 64a
Beuning PJ, Fang JS, Sefcikova J, et al. (2009) Regulation Of The DNA Damage Response By The DNA Polymerase Manager Protein UmuD Biophysical Journal. 96: 342a
Sefcikova J, Malcho J, Foley K, et al. (2009) Quantitative Characterization of Interactions of the Escherichia Coli SOS DNA Damage Response Proteins UmuD and UmuD' with the Replicative DNA Polymerase Biophysical Journal. 96: 341a-342a
McCauley MJ, Shokri L, Sefcikova J, et al. (2008) Distinct double- and single-stranded DNA binding of E. coli replicative DNA polymerase III alpha subunit. Acs Chemical Biology. 3: 577-87
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