Yi Wu, Ph.D.
Affiliations: | 2004 | Northwestern University, Evanston, IL |
Area:
molecular mechanisms of metastasisGoogle:
"Yi Wu"Parents
Sign in to add mentor| M. Sharon Stack | grad student | 2004 | Northwestern | |
| (Dynamic regulation of membrane type 1-matrix metalloproteinase.) | ||||
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Publications
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| Moss NM, Wu YI, Liu Y, et al. (2009) Modulation of the membrane type 1 matrix metalloproteinase cytoplasmic tail enhances tumor cell invasion and proliferation in three-dimensional collagen matrices. The Journal of Biological Chemistry. 284: 19791-9 |
| Wu YI, Munshi HG, Snipas SJ, et al. (2007) Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking. The Biochemical Journal. 407: 171-7 |
| Wolf K, Wu YI, Liu Y, et al. (2007) Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nature Cell Biology. 9: 893-904 |
| Munshi HG, Wu YI, Mukhopadhyay S, et al. (2004) Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis. The Journal of Biological Chemistry. 279: 39042-50 |
| Tam EM, Morrison CJ, Wu YI, et al. (2004) Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substrates. Proceedings of the National Academy of Sciences of the United States of America. 101: 6917-22 |
| Wu YI, Munshi HG, Sen R, et al. (2004) Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase. The Journal of Biological Chemistry. 279: 8278-89 |
| Munshi HG, Wu YI, Ariztia EV, et al. (2002) Calcium regulation of matrix metalloproteinase-mediated migration in oral squamous cell carcinoma cells. The Journal of Biological Chemistry. 277: 41480-8 |
| Tam EM, Wu YI, Butler GS, et al. (2002) Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage. The Journal of Biological Chemistry. 277: 39005-14 |
| Munshi HG, Ghosh S, Mukhopadhyay S, et al. (2002) Proteinase suppression by E-cadherin-mediated cell-cell attachment in premalignant oral keratinocytes. The Journal of Biological Chemistry. 277: 38159-67 |
| Ghosh S, Wu Y, Stack MS. (2002) Ovarian cancer-associated proteinases. Cancer Treatment and Research. 107: 331-51 |