Lewis Libman Engel
Affiliations: | Harvard University, Cambridge, MA, United States |
Area:
Steroid HormonesWebsite:
http://www.universitystory.gla.ac.uk/biography/?id=WH2265&type=PGoogle:
"Lewis Libman Engel"Bio:
(1909 - 1978)
http://dx.doi.org/10.1210/endo-104-2-563
Chair, Harvard Dept. Biological Chemistry
Cross-listing: Neurotree
Parents
Sign in to add mentor| Hans Thacher Clarke | grad student | 1936 | Columbia | |
| (The constitution of osazones) | ||||
| Leopold Ružička | post-doc | 1935-1936 | ETH Zürich | |
Children
Sign in to add trainee| Allan Munck | grad student | 1956 | MIT |
| Harry J. Karavolas | post-doc | 1968 | Harvard |
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Publications
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| Inano H, Engel LL. (1980) Photoaffinity labeling of human placental estradiol dehydrogenase with 3-(arylazido-beta-alanine)estrone. The Journal of Biological Chemistry. 255: 7694-9 |
| Engel LL, Inano H. (1978) Some kinetic properties of human placental estradiol-17 beta dehydrogenase: patterns of inhibition by adenine nucleotides. Advances in Enzyme Regulation. 17: 363-71 |
| Groman EV, Engel LL. (1977) Hydroxysteroid dehydrogenases of Pseudomonas testosteroni. Separation of a 17 beta-hydroxysteroid dehydrogenase from the 3(17) beta-hydroxysteroid dehydrogenase and comparison of the two enzymes. Biochimica Et Biophysica Acta. 485: 249-54 |
| Schultz RM, Groman EV, Engel LL. (1977) 3(17)beta-Hydroxysteroid dehydrogenase of Pseudomonas testosteroni. A convenient purification and demonstration of multiple molecular forms. The Journal of Biological Chemistry. 252: 3775-83 |
| Groman EV, Schultz RM, Engel LL, et al. (1976) Horse-liver alcohol dehydrogenase and Pseudomonas testosteroni 3(17)beta-hydroxysteroid dehydrogenase transfer epimeric hydrogens from NADH to 17beta-hydroxy-5alpha-androstan-3-one. An exception to one of the Alworth-Bentley rules. European Journal of Biochemistry / Febs. 63: 427-9 |
| Groman EV, Schultz RM, Engel LL. (1975) Catalytic competence, a new criterion for affinity labeling. Demonstration of the reversible enzymatic interconversion of estrone and estradiol-17 beta covalently bound to human placental estradiol-17 beta dehydrogenase. The Journal of Biological Chemistry. 250: 5450-4 |
| Engel LL, Groman EV. (1974) Human placental 17beta-estradiol dehydrogenase: characterization and structural studies. Recent Progress in Hormone Research. 30: 139-69 |
| Engel LL, Schultz RM, Groman EV. (1974) Proceedings: Human placental oestradiol-17beta dehydrogenase affinity labelled at the active region. The Journal of Endocrinology. 63: 58P |
| Ford HC, Engel LL. (1974) Purification and properties of the delta 5-3 beta-hydroxysteroid dehydrogenase-isomerase system of sheep adrenal cortical microsomes. The Journal of Biological Chemistry. 249: 1363-8 |
| Braselton WE, Engel LL, Orr JC. (1974) The flux of intermediates and products in aromatizaton of C19 steroids by human placental microsomes. European Journal of Biochemistry / Febs. 48: 35-43 |