James C. Sacchettini

Affiliations: 
Texas A & M University, College Station, TX, United States 
Area:
Biochemistry
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"James Sacchettini"

Children

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Donald R. Ronning grad student (Microtree)
Lance W. Shipman grad student 2001 Texas A & M
Mack R. Kuo grad student 2006 Texas A & M
Arati Ramesh grad student 2007 Texas A & M
Sanghamitra Dey grad student 2008 Texas A & M
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Publications

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Qu D, Ge P, Botella L, et al. (2024) Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin. Nature Communications. 15: 4161
Krieger IV, Yalamanchili S, Dickson P, et al. (2024) Inhibitors of the Thioesterase Activity of Pks13 Discovered Using DNA-Encoded Chemical Library Screening. Acs Infectious Diseases
Singh A, Ottavi S, Krieger I, et al. (2024) Redirecting raltitrexed from cancer cell thymidylate synthase to phosphopantetheinyl transferase. Science Advances. 10: eadj6406
Singh V, Grzegorzewicz AE, Fienberg S, et al. (2022) 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in . Acs Infectious Diseases. 8: 2315-2326
Khan D, Lee D, Gulten G, et al. (2020) A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins. Elife. 9
Lopez Quezada L, Smith R, Lupoli TJ, et al. (2020) Activity-Based Protein Profiling Reveals That Cephalosporins Selectively Active on Non-replicating Bind Multiple Protein Families and Spare Peptidoglycan Transpeptidases. Frontiers in Microbiology. 11: 1248
Krieger I, Kuznetsov V, Chang JY, et al. (2020) The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition. Journal of Molecular Biology
Jansen RS, Mandyoli L, Hughes R, et al. (2020) Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis. Nature Communications. 11: 1960
Taira J, Umei T, Inoue K, et al. (2020) Improvement of the novel inhibitor for Mycobacterium enoyl-acyl carrier protein reductase (InhA): a structure-activity relationship study of KES4 assisted by in silico structure-based drug screening. The Journal of Antibiotics
Sun Q, Li X, Perez LM, et al. (2020) The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD. Nature Communications. 11: 339
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