Thomas D. Niehaus, Ph.D.

Affiliations: 
2011 Plant and Soil Sciences University of Kentucky, Lexington, KY 
Area:
Botany Biology, Molecular Biology, Biochemistry, Plant Culture Agriculture
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"Thomas Niehaus"

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Joe Chappell grad student 2011 University of Kentucky
 (Elucidating the biochemical wizardry of triterpene metabolism in Botroycoccus braunii.)
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Publications

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Wissbroecker KB, Zmuda AJ, Karumanchi H, et al. (2024) Biochemical and genomic evidence for converging metabolic routes of metformin and biguanide breakdown in environmental Pseudomonads. The Journal of Biological Chemistry. 107935
Zmuda AJ, Kang X, Wissbroecker KB, et al. (2024) A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle. Nature Communications. 15: 846
Zmuda AJ, Niehaus TD. (2022) Systems and strategies for plant protein expression. Methods in Enzymology. 680: 3-34
Hillmann KB, Goethel ME, Erickson NA, et al. (2022) Identification of a S-(2-succino)cysteine breakdown pathway that uses a novel S-(2-succino) lyase. The Journal of Biological Chemistry. 102639
Niehaus TD, Hillmann KB. (2020) Enzyme promiscuity, metabolite damage, and metabolite damage control systems of the tricarboxylic acid cycle. The Febs Journal
Niehaus TD, Patterson JA, Alexander DC, et al. (2019) The metabolite repair enzyme Nit1 is a dual-targeted amidase that disposes of damaged glutathione in . The Biochemical Journal
Hanson AD, Amthor JS, Sun J, et al. (2018) Redesigning thiamin synthesis: Prospects and potential payoffs. Plant Science : An International Journal of Experimental Plant Biology. 273: 92-99
Paerl RW, Bertrand EM, Rowland E, et al. (2018) Carboxythiazole is a key microbial nutrient currency and critical component of thiamin biosynthesis. Scientific Reports. 8: 5940
Niehaus TD, Elbadawi-Sidhu M, Huang L, et al. (2018) Evidence that the metabolite repair enzyme NAD(P)HX epimerase has a moonlighting function. Bioscience Reports
Niehaus TD, Folz J, McCarty DR, et al. (2018) Identification of a metabolic disposal route for the oncometabolite-(2-succino)cysteine in. The Journal of Biological Chemistry
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