Daniel E. Gottschling

Affiliations: 
Fred Hutchinson Cancer Research Center, Seattle, WA, United States 
Area:
cellular aging
Website:
http://labs.fhcrc.org/gottschling/
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"Daniel E. Gottschling"
Bio:

http://www.nasonline.org/member-directory/members/20024835.html

Cross-listing: Telomere and Telomerase Tree

Parents

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Thomas R. Cech grad student 1984 CU Boulder
 (Chromatin structure and chromosomal function : Tetrahymena thermophila and Oxytricha nova as model systems)
Virginia A. Zakian post-doc Fred Hutchinson Cancer Center
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Publications

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Goodrum JM, Lever AR, Coody TK, et al. (2019) Rsp5 and Mdm30 reshape the mitochondrial network in response to age-induced vacuole stress. Molecular Biology of the Cell. mbcE19020094
Hughes AL, Hughes CE, Henderson KA, et al. (2016) Author response: Selective sorting and destruction of mitochondrial membrane proteins in aged yeast Elife
Thayer NH, Leverich CK, Fitzgibbon MP, et al. (2014) Identification of long-lived proteins retained in cells undergoing repeated asymmetric divisions. Proceedings of the National Academy of Sciences of the United States of America. 111: 14019-26
Dillin A, Gottschling DE, Nyström T. (2014) The good and the bad of being connected: the integrons of aging. Current Opinion in Cell Biology. 26: 107-12
Hughes AL, Gottschling DE. (2012) An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast. Nature. 492: 261-5
Dymond JS, Richardson SM, Coombes CE, et al. (2011) Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature. 477: 471-6
Lindstrom DL, Leverich CK, Henderson KA, et al. (2011) Replicative age induces mitotic recombination in the ribosomal RNA gene cluster of Saccharomyces cerevisiae. Plos Genetics. 7: e1002015
Verzijlbergen KF, Menendez-Benito V, van Welsem T, et al. (2010) Recombination-induced tag exchange to track old and new proteins. Proceedings of the National Academy of Sciences of the United States of America. 107: 64-8
Lindstrom DL, Gottschling DE. (2009) The mother enrichment program: a genetic system for facile replicative life span analysis in Saccharomyces cerevisiae. Genetics. 183: 413-22, 1SI-13SI
Dimitrov LN, Brem RB, Kruglyak L, et al. (2009) Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains. Genetics. 183: 365-83
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