Alexey E. Granovsky, Ph.D.
Affiliations: | 2002 | University of Iowa, Iowa City, IA |
Area:
Molecular Biology, BiochemistryGoogle:
"Alexey Granovsky"Parents
Sign in to add mentor| Nikolai O. Artemyev | grad student | 2002 | University of Iowa | |
| (Function and regulation of photoreceptor cGMP phosphodiesterase.) | ||||
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Publications
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| Shemon AN, Heil GL, Granovsky AE, et al. (2010) Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands. Plos One. 5: e10479 |
| Granovsky AE, Clark MC, McElheny D, et al. (2009) Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism. Molecular and Cellular Biology. 29: 1306-20 |
| Muradov KG, Granovsky AE, Artemyev NO. (2003) Mutation in rod PDE6 linked to congenital stationary night blindness impairs the enzyme inhibition by its gamma-subunit. Biochemistry. 42: 3305-10 |
| Muradov KG, Granovsky AE, Schey KL, et al. (2002) Direct interaction of the inhibitory gamma-subunit of Rod cGMP phosphodiesterase (PDE6) with the PDE6 GAFa domains. Biochemistry. 41: 3884-90 |
| Granovsky AE, Artemyev NO. (2002) Assays of G protein/cGMP-phosphodiesterase interactions. Methods in Enzymology. 345: 27-37 |
| Granovsky AE, Artemyev NO. (2001) A conformational switch in the inhibitory gamma-subunit of PDE6 upon enzyme activation by transducin. Biochemistry. 40: 13209-15 |
| Granovsky AE, Artemyev NO. (2001) Partial reconstitution of photoreceptor cGMP phosphodiesterase characteristics in cGMP phosphodiesterase-5. The Journal of Biological Chemistry. 276: 21698-703 |
| Granovsky AE, Artemyev NO. (2000) Identification of the gamma subunit-interacting residues on photoreceptor cGMP phosphodiesterase, PDE6alpha '. The Journal of Biological Chemistry. 275: 41258-62 |
| Granovsky AE, Muradov KG, Artemyev NO. (2000) Inhibition of photoreceptor cGMP phosphodiesterase by its gamma subunit. Methods in Enzymology. 315: 635-46 |
| Natochin M, Granovsky AE, Muradov KG, et al. (1999) Roles of the transducin alpha-subunit alpha4-helix/alpha4-beta6 loop in the receptor and effector interactions. The Journal of Biological Chemistry. 274: 7865-9 |