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Karol S. Bruzik

Affiliations: 
University of Illinois at Chicago, Health Sciences Center, Chicago, IL 60612, United States 
Area:
Biochemistry
Website:
https://pharmacy.uic.edu/people-resources/directory/kbruzik
Google:
"Karol S Bruzik"
Bio:

https://mcp.uic.edu/people/bruzik_ks.html

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Parents

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Ming-Daw Tsai post-doc 1981-1983 Ohio State

Children

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Cornelia Mihai grad student 2001 University of Illinois at Chicago, Health Sciences Center
Chuan Bai grad student 2010 University of Illinois at Chicago, Health Sciences Center

Collaborators

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Publications

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Jayakar SS, Chiara DC, Zhou X, et al. (2020) Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABA) receptors. The Journal of Biological Chemistry
Savechenkov PY, Chiara DC, Desai R, et al. (2017) Synthesis and pharmacological evaluation of neurosteroid photoaffinity ligands. European Journal of Medicinal Chemistry. 136: 334-347
Chiara DC, Jounaidi Y, Zhou X, et al. (2016) General Anesthetic Binding Sites in Human α4β3δ γ-Aminobutyric Acid Type-A Receptors (GABAAR). The Journal of Biological Chemistry
Chiara DC, Savechenkov PY, Zhou X, et al. (2016) Interactions of a Photoreactive Steroid Anesthetic (F4N3-Alphaxalone) with Human α1β3γ2 GABA-A Receptors Biophysical Journal. 110: 455a
Desai R, Savechenkov PY, Zolkowska D, et al. (2015) Contrasting actions of a convulsant barbiturate and its anti-convulsant enantiomer on the α1β3γ2L GABAA receptor account for their in vivo effects. The Journal of Physiology
Jayakar SS, Zhou X, Savechenkov PY, et al. (2015) Positive and Negative Allosteric Modulation of an α1β3γ2 γ-Aminobutyric acid Type A (GABAA) Receptor by Binding to a Site in the Transmembrane Domain at the γ+-β- Interface. The Journal of Biological Chemistry
Jayakar SS, Zhou X, Chiara DC, et al. (2014) Multiple propofol-binding sites in a γ-aminobutyric acid type A receptor (GABAAR) identified using a photoreactive propofol analog. The Journal of Biological Chemistry. 289: 27456-68
Hamouda AK, Stewart DS, Chiara DC, et al. (2014) Identifying barbiturate binding sites in a nicotinic acetylcholine receptor with [3H]allyl m-trifluoromethyldiazirine mephobarbital, a photoreactive barbiturate. Molecular Pharmacology. 85: 735-46
Chiara DC, Jayakar SS, Zhou X, et al. (2013) Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor. The Journal of Biological Chemistry. 288: 19343-57
Shanmugasundararaj S, Das J, Sandberg WS, et al. (2012) Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cδ*. Biophysical Journal. 103: 2331-40
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