David M. Karnak, Ph.D.
Affiliations: | 2004 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
BiochemistryGoogle:
"David Karnak"Parents
Sign in to add mentor| Benjamin L. Margolis | grad student | 2004 | University of Michigan | |
| (Biochemical and structural studies of the LIN-2 and 7 (L27) dimerization domain: Linking proteins important to cell polarity.) | ||||
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Publications
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| Valvo VM, Zhang Q, Jiang L, et al. (2024) Olaparib and Radiotherapy Induce Type I Interferon- and CD8+ T Cell-Dependent Sensitization to Immunotherapy in Pancreatic Cancer. Molecular Cancer Therapeutics. OF1-OF16 |
| Wang W, McMillan MT, Zhao X, et al. (2022) DNA-PK inhibition and radiation promote anti-tumoral immunity through RNA Polymerase III in pancreatic cancer. Molecular Cancer Research : McR |
| Parsels LA, Zhang Q, Karnak D, et al. (2021) Translation of DNA damage response inhibitors as chemoradiation sensitizers from the laboratory to the clinic. International Journal of Radiation Oncology, Biology, Physics |
| Cuneo KC, Devasia T, Sun Y, et al. (2019) Serum Levels of Hepatocyte Growth Factor and CD40 Ligand Predict Radiation-Induced Liver Injury. Translational Oncology. 12: 889-894 |
| Chefetz I, Grimley E, Yang K, et al. (2019) A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Reports. 26: 3061-3075.e6 |
| Jackson WC, Hartman HE, Gharzai LA, et al. (2019) A Mid-Treatment Increase in Albi Score Is Strongly Associated with Treatment Related Toxicity Following Liver Radiation Therapy International Journal of Radiation Oncology Biology Physics. 105 |
| Cuneo KC, Devasia TP, Karnak D, et al. (2019) Tumor Necrosis Factor Receptor 1 Levels Predict Radiation Induced Liver Injury International Journal of Radiation Oncology Biology Physics. 105 |
| Parsels LA, Karnak D, Parsels J, et al. (2017) PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors. Molecular Cancer Research : McR |
| Cuneo KC, Morgan MA, Davis MA, et al. (2016) Wee1 Kinase Inhibitor AZD1775 Radiosensitizes Hepatocellular Carcinoma Regardless of TP53 Mutational Status Through Induction of Replication Stress. International Journal of Radiation Oncology, Biology, Physics |
| Zhang Q, Karnak D, Tan M, et al. (2016) FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4. Molecular Cell |