Michele C. Kieke, Ph.D.
Affiliations: | 2001 | University of Illinois, Urbana-Champaign, Urbana-Champaign, IL |
Area:
Immunology, BiochemistryGoogle:
"Michele Kieke"Parents
Sign in to add mentor| David Michael Kranz | grad student | 2001 | UIUC | |
| (Directed evolution of T cell receptor antagonists.) | ||||
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Publications
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| Cho S, Swaminathan CP, Bonsor DA, et al. (2010) Assessing energetic contributions to binding from a disordered region in a protein-protein interaction . Biochemistry. 49: 9256-68 |
| Cho S, Swaminathan CP, Yang J, et al. (2005) Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure (London, England : 1993). 13: 1775-87 |
| Yang J, Swaminathan CP, Huang Y, et al. (2003) Dissecting cooperative and additive binding energetics in the affinity maturation pathway of a protein-protein interface. The Journal of Biological Chemistry. 278: 50412-21 |
| Kieke MC, Sundberg E, Shusta EV, et al. (2001) High affinity T cell receptors from yeast display libraries block T cell activation by superantigens. Journal of Molecular Biology. 307: 1305-15 |
| Shusta EV, Holler PD, Kieke MC, et al. (2000) Directed evolution of a stable scaffold for T-cell receptor engineering. Nature Biotechnology. 18: 754-9 |
| Shusta EV, Kieke MC, Parke E, et al. (1999) Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency. Journal of Molecular Biology. 292: 949-56 |
| Kieke MC, Shusta EV, Boder ET, et al. (1999) Selection of functional T cell receptor mutants from a yeast surface-display library. Proceedings of the National Academy of Sciences of the United States of America. 96: 5651-6 |
| Cho BK, Kieke MC, Boder ET, et al. (1998) A yeast surface display system for the discovery of ligands that trigger cell activation. Journal of Immunological Methods. 220: 179-88 |
| Kieke MC, Cho BK, Boder ET, et al. (1997) Isolation of anti-T cell receptor scFv mutants by yeast surface display. Protein Engineering. 10: 1303-10 |