John F. Teiber, Ph.D.

Affiliations: 
2000 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Toxicology, Molecular Biology
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"John Teiber"

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Paul F. Hollenberg grad student 2000 University of Michigan
 (Metabolism of N-nitrosodi-n-propylamine and its oxidized derivatives.)
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Publications

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Teiber JF, Xiao J, Kramer GL, et al. (2018) Identification of biologically active δ-lactone eicosanoids as paraoxonase substrates. Biochemical and Biophysical Research Communications
Ebert J, Wilgenbus P, Teiber JF, et al. (2018) Paraoxonase-2 regulates coagulation activation through endothelial tissue factor. Blood
Horke S, Xiao J, Schütz EM, et al. (2015) A novel paraoxonase 2-dependent mechanism mediating the biological effects of the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxo-dodecanoyl)-L-homoserine lactone. Infection and Immunity
Schweikert EM, Amort J, Wilgenbus P, et al. (2012) Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties. Journal of Lipids. 2012: 352857
Schweikert EM, Devarajan A, Witte I, et al. (2012) PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death. Cell Death and Differentiation. 19: 1549-60
Connelly PW, Picardo CM, Potter PM, et al. (2011) Mouse serum paraoxonase-1 lactonase activity is specific for medium-chain length fatty acid lactones. Biochimica Et Biophysica Acta. 1811: 39-45
Teiber JF, Draganov DI. (2011) High-performance liquid chromatography analysis of N-acyl homoserine lactone hydrolysis by paraoxonases. Methods in Molecular Biology (Clifton, N.J.). 692: 291-8
Altenhöfer S, Witte I, Teiber JF, et al. (2010) One enzyme, two functions: PON2 prevents mitochondrial superoxide formation and apoptosis independent from its lactonase activity. The Journal of Biological Chemistry. 285: 24398-403
Draganov D, Teiber J, Watson C, et al. (2010) PON1 and oxidative stress in human sepsis and an animal model of sepsis. Advances in Experimental Medicine and Biology. 660: 89-97
Horke S, Witte I, Altenhöfer S, et al. (2010) Paraoxonase 2 is down-regulated by the Pseudomonas aeruginosa quorumsensing signal N-(3-oxododecanoyl)-L-homoserine lactone and attenuates oxidative stress induced by pyocyanin. The Biochemical Journal. 426: 73-83
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