Wenying Jian, Ph.D.

Affiliations: 
2005 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Pharmacology
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"Wenying Jian"

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Ian A. Blair grad student 2005 Penn
 (Lipid peroxidation-derived endogenous DNA- and GSH-adducts as biomarkers of oxidative stress.)
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Publications

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Wojcik J, Sikorski T, Wang J, et al. (2025) 2024 White Paper on Recent Issues in Bioanalysis: Three Way-Cross Validation; Urine Clinical Analysis; Automated Methods; Regulatory Queries on Plasma Protein Binding; Automated Biospecimen Management; ELN Migration; Ultra-Sensitivity Mass Spectrometry ( - Recommendations on Advanced Strategies for Mass Spectrometry Assays, Chromatography, Sample Preparation and BMV/Regulated Bioanalysis - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV). Bioanalysis. 1-39
Baratta M, Jian W, Hengel S, et al. (2024) 2023 White Paper on Recent Issues in Bioanalysis: Deuterated Drugs; LNP; Tumor/FFPE Biopsy; Targeted Proteomics; Small Molecule Covalent Inhibitors; Chiral Bioanalysis; Remote Regulatory Assessments; Sample Reconciliation/Chain of Custody - Recommendations on Mass Spectrometry, Chromatography, Sample Preparation Latest Developments, Challenges, and Solutions and BMV/Regulated Bioanalysis - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/IVD/CDx/BAV, Immunogenicity, Gene & Cell Therapy and Vaccine). Bioanalysis. 16: 307-364
Szapacs M, Jian W, Spellman D, et al. (2023) 2022 White Paper on Recent Issues in Bioanalysis: ICH M10 BMV Guideline & Global Harmonization; Hybrid Assays; Oligonucleotides & ADC; Non-Liquid & Rare Matrices; Regulatory Inputs ( - Recommendations on Mass Spectrometry, Chromatography and Sample Preparation, Novel Technologies, Novel Modalities, and Novel Challenges, ICH M10 BMV Guideline & Global Harmonization - Regulatory Agencies' Inputs on Regulated Bioanalysis/BMV, Biomarkers/CDx/BAV, Immunogenicity, Gene & Cell Therapy and Vaccine). Bioanalysis
Kaur S, Alley SC, Szapacs M, et al. (2022) 2021 White Paper on Recent Issues in Bioanalysis: Mass Spec of Proteins, Extracellular Vesicles, CRISPR, Chiral Assays, Oligos; Nanomedicines Bioanalysis; ICH M10 Section 7.1; Non-Liquid & Rare Matrices; Regulatory Inputs ( - Recommendations on Endogenous Compounds, Small Molecules, Complex Methods, Regulated Mass Spec of Large Molecules, Small Molecule, PoC &  - Regulatory Agencies' Inputs on Bioanalysis, Biomarkers, Immunogenicity, Gene & Cell Therapy and Vaccine). Bioanalysis. 14: 505-580
Walles M, Berna MJ, Jian W, et al. (2022) . Drug Metabolism and Disposition: the Biological Fate of Chemicals
Khojasteh SC, Argikar UA, Driscoll JP, et al. (2021) Novel Advances in Biotransformation and Bioactivation Research - 2020 year in review. Drug Metabolism Reviews. 1-91
Neubert H, Alley SC, Lee A, et al. (2021) 2020 White Paper on Recent Issues in Bioanalysis: BMV of Hybrid Assays, Acoustic MS, HRMS, Data Integrity, Endogenous Compounds, Microsampling and Microbiome ( - Recommendations on Industry/Regulators Consensus on BMV of Biotherapeutics by LCMS, Advanced Application in Hybrid Assays, Regulatory Challenges in Mass Spec, Innovation in Small Molecules, Peptides and Oligos). Bioanalysis
Kang L, Weng N, Jian W. (2019) LC-MS bioanalysis of intact proteins and peptides. Biomedical Chromatography : Bmc. e4633
Weng N, Jian W. (2018) Selectivity for quantitation of biomarkers using liquid chromatography and mass spectrometry. Bioanalysis
Kang L, Connolly TM, Weng N, et al. (2017) LC-MS/MS quantification of 7α-hydroxy-4-cholesten-3-one (C4) in rat and monkey plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1064: 49-55
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