Vasudha Sharma, Ph.D.

Affiliations: 
2006 Michigan State University, East Lansing, MI 
Area:
Organic Chemistry, Biochemistry, Pharmaceutical Chemistry
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"Vasudha Sharma"

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Jetze J. Tepe grad student 2006 Michigan State
 (Strategic improvements in efficacy of DNA damaging chemotherapeutic drugs through modulation of survival factors.)
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Publications

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Sharma V, Hupp CD, Tepe JJ. (2007) Enhancement of chemotherapeutic efficacy by small molecule inhibition of NF-kappaB and checkpoint kinases. Current Medicinal Chemistry. 14: 1061-74
Sharma V, Peddibhotla S, Tepe JJ. (2006) Sensitization of cancer cells to DNA damaging agents by imidazolines. Journal of the American Chemical Society. 128: 9137-43
Sharma V, Tepe JJ. (2005) Diastereochemical diversity of imidazoline scaffolds via substrate controlled TMSCl mediated cycloaddition of azlactones. Organic Letters. 7: 5091-4
Sharma V, Lansdell TA, Peddibhotla S, et al. (2004) Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines. Chemistry & Biology. 11: 1689-99
Sharma V, Tepe JJ. (2004) Potent inhibition of checkpoint kinase activity by a hymenialdisine-derived indoloazepine. Bioorganic & Medicinal Chemistry Letters. 14: 4319-21
Sharma V, Lansdell TA, Jin G, et al. (2004) Inhibition of cytokine production by hymenialdisine derivatives. Journal of Medicinal Chemistry. 47: 3700-3
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