Stan Lipkowitz

Affiliations: 
Biochemistry and Molecular Genetics The George Washington University, Washington, DC, United States 
Area:
Molecular Biology, Cell Biology
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"Stan Lipkowitz"
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Publications

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Daniels SR, Liyasova M, Kales SC, et al. (2019) Loss of function Cbl-c mutations in solid tumors. Plos One. 14: e0219143
Liyasova MS, Ma K, Voeller D, et al. (2019) Cbl interacts with multiple E2s in vitro and in cells. Plos One. 14: e0216967
Li M, Kales SC, Ma K, et al. (2015) Balancing protein stability and activity in cancer: a new approach for identifying driver mutations affecting CBL ubiquitin ligase activation. Cancer Research
Liyasova MS, Ma K, Lipkowitz S. (2015) Molecular pathways: cbl proteins in tumorigenesis and antitumor immunity-opportunities for cancer treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1789-94
Kales SC, Nau MM, Merchant AS, et al. (2014) Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A Plos One. 9
Ma K, Kales SC, Nau MM, et al. (2013) Cbl as a master regulator of receptor tyrosine Kinase trafficking Vesicle Trafficking in Cancer. 2147483647: 219-244
Ryan PE, Kales SC, Yadavalli R, et al. (2012) Cbl-c ubiquitin ligase activity is increased via the interaction of its RING finger domain with a LIM domain of the paxillin homolog, Hic 5. Plos One. 7: e49428
Kales SC, Ryan PE, Lipkowitz S. (2012) Cbl exposes its RING finger. Nature Structural & Molecular Biology. 19: 131-3
Lipkowitz S, Weissman AM. (2011) RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis Nature Reviews Cancer. 11: 629-643
Ryan PE, Sivadasan-Nair N, Nau MM, et al. (2010) The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme Journal of Biological Chemistry. 285: 23687-23698
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