Kathryn M. Ferguson
Affiliations: | Biochemistry and Molecular Biophysics | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Biochemistry, Molecular BiologyWebsite:
http://www.med.upenn.edu/apps/faculty/index.php/g20/p12430Google:
"Kathryn Ferguson"Cross-listing: Physiology Academic Tree
Parents
Sign in to add mentor| Paul B. Sigler | grad student | 1996 | Yale | |
| (Pleckstrin homology domains: structure and ligand binding.) | ||||
Children
Sign in to add trainee| Karl R. Schmitz | grad student | 2010 | Penn |
| Yu-San Huoh | grad student | 2013 | Penn |
| Atrish Bagchi | grad student | 2012-2016 | University of Pennsylvania School of Medicine |
BETA: Related publications
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Publications
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| Bagchi A, Stayrook SE, Xenaki KT, et al. (2024) Structural insights into the role and targeting of EGFRvIII. Structure (London, England : 1993) |
| Hu C, Leche CA, Kiyatkin A, et al. (2022) Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias. Nature. 602: 518-522 |
| Ferguson KM, Hu C, Lemmon MA. (2020) Insulin and EGF receptor family members share parallel activation mechanisms. Protein Science : a Publication of the Protein Society |
| Emptage RP, Lemmon MA, Ferguson KM, et al. (2018) Structural Basis for MARK1 Kinase Autoinhibition by Its KA1 Domain. Structure (London, England : 1993). 26: 1137-1143.e3 |
| Bagchi A, Haidar JN, Eastman SW, et al. (2017) Molecular basis for necitumumab inhibition of EGFR variants associated with acquired cetuximab resistance. Molecular Cancer Therapeutics |
| Freed DM, Bessman NJ, Kiyatkin A, et al. (2017) EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics. Cell |
| Emptage RP, Schoenberger MJ, Ferguson KM, et al. (2017) Intramolecular autoinhibition of Checkpoint Kinase 1 is mediated by conserved basic motifs of the C-terminal Kinase Associated-1 domain. The Journal of Biological Chemistry |
| Moore JO, Lemmon MA, Ferguson KM. (2017) Dimerization of Tie2 mediated by its membrane-proximal FNIII domains. Proceedings of the National Academy of Sciences of the United States of America |
| Emptage RP, Lemmon MA, Ferguson KM. (2016) Molecular determinants of KA1 domain-mediated autoinhibition and phospholipid activation of MARK1 kinase. The Biochemical Journal |
| Moravcevic K, Alvarado D, Schmitz KR, et al. (2015) Comparison of Saccharomyces cerevisiae F-BAR domain structures reveals a conserved inositol phosphate binding site. Structure (London, England : 1993). 23: 352-63 |