Nicholas E. Hoffman, Ph.D.
Affiliations: | 2014 | Biochemistry | Temple University, Philadelphia, PA, United States |
Area:
BiochemistryGoogle:
"Nicholas Hoffman"Parents
Sign in to add mentor| Madesh Muniswamy | grad student | 2014 | Temple University | |
| (Mitochondrial calcium influx is determined by multiple protein components including SLC25A23 and MICU1.) | ||||
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Publications
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| Joseph LC, Kokkinaki D, Valenti MC, et al. (2017) Inhibition of NADPH oxidase 2 (NOX2) prevents sepsis-induced cardiomyopathy by improving calcium handling and mitochondrial function. Jci Insight. 2 |
| Tomar D, Dong Z, Shanmughapriya S, et al. (2016) MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics. Cell Reports |
| Zhou J, Ahmad F, Parikh S, et al. (2016) Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy. Circulation Research |
| Feldman AM, Gordon J, Wang J, et al. (2016) BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes. Journal of Molecular and Cellular Cardiology |
| Shanmughapriya S, Rajan S, Hoffman NE, et al. (2015) SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore. Molecular Cell. 60: 47-62 |
| Shanmughapriya S, Rajan S, Hoffman NE, et al. (2015) Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. Science Signaling. 8: ra23 |
| Hoffman NE, Miller BA, Wang J, et al. (2015) Ca²⁺ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance. American Journal of Physiology. Heart and Circulatory Physiology. 308: H637-50 |
| Doonan PJ, Chandramoorthy HC, Hoffman NE, et al. (2014) LETM1-dependent mitochondrial Ca2+ flux modulates cellular bioenergetics and proliferation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4936-49 |
| Makarewich CA, Zhang H, Davis J, et al. (2014) Transient receptor potential channels contribute to pathological structural and functional remodeling after myocardial infarction. Circulation Research. 115: 567-80 |
| Brailoiu GC, Deliu E, Marcu J, et al. (2014) Differential activation of intracellular versus plasmalemmal CB2 cannabinoid receptors. Biochemistry. 53: 4990-9 |