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Harinath Chakrapani, Ph.D.

Affiliations: 
2009- Chemistry IISER Pune, Pune, Maharashtra, India 
Area:
organic chemistry, chemical biology, nitric oxide, reactive oxygen species, redox biology
Website:
www.hclab.in
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"Harinath Chakrapani"
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Parents

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Eric J. Toone grad student 2005
S. Bruce King post-doc

Children

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Sharath Chandra Mallojjala research assistant 2011-2015 Indian Institute of Science Education and Research (IISER) Pune
Dharmaraja Allimuthu grad student 2010-2014 IISER Pune
Vinayak Khodade grad student 2010-2015 IISER Pune
Kavita Sharma grad student 2010-2015 IISER Pune
Ajay Kumar Sharma grad student 2019 IISER Pune
Ravikumar Govindan grad student 2013-2019 IISER Pune
Amogh Kulkarni grad student 2014-2019 IISER Pune

Collaborators

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Publications

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Sarkar UD, Rana M, Chakrapani H. (2024) Phenacylselenoesters allow facile selenium transfer and hydrogen selenide generation. Chemical Science. 15: 19315-19321
Dewan A, Jain C, Das M, et al. (2024) Intracellular peroxynitrite perturbs redox balance, bioenergetics, and Fe-S cluster homeostasis in Mycobacterium tuberculosis. Redox Biology. 75: 103285
Sawase LR, Kumar TA, Mathew AB, et al. (2023) β-Galactosidase-activated nitroxyl (HNO) donors provide insights into redox cross-talk in senescent cells. Chemical Communications (Cambridge, England). 59: 12751-12754
Bora P, Sathian MB, Chakrapani H. (2022) Enhancing cellular sulfane sulfur through β-glycosidase-activated persulfide donors: mechanistic insights and oxidative stress mitigation. Chemical Communications (Cambridge, England)
Bora P, Manna S, Nair MA, et al. (2021) Leveraging an enzyme/artificial substrate system to enhance cellular persulfides and mitigate neuroinflammation. Chemical Science. 12: 12939-12949
Khandelwal N, Shaikh M, Mhetre A, et al. (2021) Fatty acid chain length drives lysophosphatidylserine-dependent immunological outputs. Cell Chemical Biology
Malwal S, Pardeshi KA, Chakrapani H. (2019) Synthesis and evaluation of cyclic sulfite diesters as sulfur dioxide (SO2) donors. Chembiochem : a European Journal of Chemical Biology
Chauhan P, Gupta K, Govindan R, et al. (2019) Carbonyl Sulfide (COS) Donor induced protein persulfidation protects against oxidative stress. Chemistry, An Asian Journal
Kulkarni A, Soni I, Kelkar D, et al. (2019) Chemoproteomics of an Indole-Based Quinone-Epoxide identifies druggable vulnerabilities in Vancomycin Resistant Staphylococcus aureus (VRSA). Journal of Medicinal Chemistry
Sharma AK, Singh H, Chakrapani H. (2019) Photocontrolled endogenous reactive oxygen species (ROS) generation. Chemical Communications (Cambridge, England)
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