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Megerditch Kiledjian

Affiliations: 
Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
Biochemistry, Molecular Biology
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"Megerditch Kiledjian"
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Nancy D. Rodgers grad student 2002 Rutgers, New Brunswick
Zuoren Wang grad student 2002 Rutgers, New Brunswick
Hudan Liu grad student 2005 Rutgers, New Brunswick
Shin-Wu Liu grad student 2007 Rutgers, New Brunswick

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Publications

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Husain RA, Jiao X, Hennings JC, et al. (2023) Biallelic NUDT2 variants defective in mRNA decapping cause a neurodevelopmental disease. Brain : a Journal of Neurology
Sharma S, Yang J, Favate J, et al. (2023) NADcapPro and circNC: methods for accurate profiling of NAD and non-canonical RNA caps in eukaryotes. Communications Biology. 6: 406
Depaix A, Grudzien-Nogalska E, Fedorczyk B, et al. (2022) Preparation of RNAs with non-canonical 5' ends using novel di- and trinucleotide reagents for co-transcriptional capping. Frontiers in Molecular Biosciences. 9: 854170
Sharma S, Yang J, Doamekpor SK, et al. (2022) Identification of a novel deFADding activity in human, yeast and bacterial 5' to 3' exoribonucleases. Nucleic Acids Research
Doamekpor SK, Sharma S, Kiledjian M, et al. (2022) Recent insights into non-canonical 5' capping and decapping of RNA. The Journal of Biological Chemistry. 102171
Sharma S, Yang J, Grudzien-Nogalska E, et al. (2022) Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA. Nature Communications. 13: 889
Salamon I, Palsule G, Luo X, et al. (2021) mRNA-Decapping Associated DcpS Enzyme Controls Critical Steps of Neuronal Development. Cerebral Cortex (New York, N.Y. : 1991)
Sahu S, Wang Z, Jiao X, et al. (2020) InsP is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics. Proceedings of the National Academy of Sciences of the United States of America
Sharma S, Grudzien-Nogalska E, Hamilton K, et al. (2020) Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs. Nucleic Acids Research
Doamekpor SK, Grudzien-Nogalska E, Mlynarska-Cieslak A, et al. (2020) DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs. Nucleic Acids Research
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