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David H. Sherman

Affiliations: 
Medicinal Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
cryptophycin anticancer drugs
Website:
http://www.cancer.med.umich.edu/news/cope-scholar09.shtml
Google:
"David Sherman"
Bio:

https://www.chem.lsa.umich.edu/chem/faculty/facultyDetail.php?Uniqname=davidhs
http://www.pharmaforensicslabs.com/home76/wp-content/uploads/2014/11/David_H_Sherman_CV.pdf

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Parents

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Phillip Crews research assistant 1975-1978 UC Santa Cruz
Gilbert Stork grad student 1982 Columbia
 (An efficient synthesis of corticosteroids)
Robert E. Handschumacher post-doc 1981-1982 Yale
Herman N. Eisen post-doc 1982-1984 MIT

Children

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Min He grad student 2000 UMN
Yun S. Kyung grad student 2000 UMN
Yingqing Mao grad student 2000 UMN
Yongquan Xue grad student 2000 UMN
Noelle J. Beyer grad student 2004 UMN
Wei Lian grad student 2005 UMN
Nathan  A. Magarvey grad student 2001-2005 UMN
Nathan  A. Magarvey grad student 2001-2005 UMN
Jeffrey L. Fortman grad student 2006 UMN
Liangcai Gu grad student 2008 University of Michigan
Shengying Li grad student 2009 University of Michigan
Tonia J. Buchholz grad student 2010 University of Michigan
Yousong Ding grad student 2010 University of Michigan
Jonathan D. Mortison grad student 2010 University of Michigan
Christopher M. Rath grad student 2011 University of Michigan
Tyler D. Nusca grad student 2012 University of Michigan
Amy E. Fraley grad student 2014-2019 University of Michigan
Alanna R Condren post-doc 2020- University of Michigan
Courtney C. Aldrich post-doc 2002-2004 UMN
Douglas Burr post-doc 2007-2009 University of Michigan
Alison Rae Narayan post-doc 2011-2015 University of Michigan
Ashootosh (Ashu) Tripathi post-doc 2012-2017 University of Michigan

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Publications

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Adrover-Castellano ML, Curtis BJ, Schmidt JJ, et al. (2025) Directed Evolution of a Modular Polyketide Synthase Thioesterase for Generation of a Hybrid Macrocyclic Ring System. Acs Catalysis. 15: 3405-3417
Rankin MR, Khare D, Gerwick L, et al. (2025) Structure of a putative terminal amidation domain in natural product biosynthesis. Structure (London, England : 1993)
Du L, Dian L, Newmister SA, et al. (2025) The Mutually Inspiring Biological and Chemical Synthesis of Fungal Bicyclo[2.2.2]diazaoctane Indole Alkaloids. Chemical Reviews
McCullough TM, Choudhary V, Akey DL, et al. (2024) Substrate Trapping in Polyketide Synthase Thioesterase Domains: Structural Basis for Macrolactone Formation. Acs Catalysis. 14: 12551-12563
Sandoval Hurtado CP, Kelly SP, Shende V, et al. (2024) Engineering a Biosynthetic Pathway for the Production of (+)-Brevianamides A and B in . Biorxiv : the Preprint Server For Biology
Pereira F, McCauley M, Lev K, et al. (2024) Optimized Production of Concanamycins Using a Rational Metabolic Engineering Strategy. Metabolic Engineering
Rankin MR, Khare D, Gerwick L, et al. (2024) Structure of a Putative Terminal Amidation Domain in Natural Product Biosynthesis. Biorxiv : the Preprint Server For Biology
Yancey CE, Hart L, Lad AC, et al. (2024) Synthesis of a Truncated Microcystin Tetrapeptide Molecule from a Partial Mcy Gene Cluster in Microcystis Cultures and Blooms. Environmental Science & Technology. 58: 19936-19947
Iizaka Y, Yamada M, Koshino S, et al. (2024) Production of hybrid macrolide antibiotics by exploiting the specific substrate recognition characteristics of multifunctional cytochrome P450 enzyme MycG. Fems Microbiology Letters. 371
Zhao C, Borotto NB, Schmidt J, et al. (2024) Gas-Phase Unfolding Reveals Stability Shifts Associated with Substrate Binding in Modular Polyketide Synthases. Journal of the American Society For Mass Spectrometry
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