Rudy E. Fuentes, Ph.D.
Affiliations: | 2010 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
PharmacologyGoogle:
"Rudy Fuentes"Parents
Sign in to add mentor| Mortimer Poncz | grad student | 2010 | Penn | |
| (Developing novel platelet-based targeting strategies for thrombolytics.) | ||||
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Publications
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| Hisada Y, Geddings JE, Boulaftali Y, et al. (2016) OC-04 - Tissue factor positive microvesicles activate platelets in vitro and in vivo and enhance thrombosis in mice. Thrombosis Research. 140: S169-70 |
| Fuentes RE, Zaitsev S, Ahn HS, et al. (2015) A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation. The Journal of Clinical Investigation |
| Geddings JE, Hisada Y, Boulaftali Y, et al. (2015) Tissue Factor-positive Tumor Microvesicles Activate Platelets and Enhance Thrombosis in Mice. Journal of Thrombosis and Haemostasis : Jth |
| Wang Y, Hayes V, Jarocha D, et al. (2015) Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale. Blood. 125: 3627-36 |
| Ahn HS, Fuentes R, Hayes V, et al. (2014) A Human-Specific, Platelet-Targeted, Thrombin-Activatable Urokinase (PLT/uPA-T) Demonstrates Selective Thromboprophylactic Properties in Two in Vivo Models Blood. 124: 579-579 |
| Lambert MP, Sullivan SK, Fuentes R, et al. (2013) Challenges and promises for the development of donor-independent platelet transfusions. Blood. 121: 3319-24 |
| Tutwiler V, Ahn HS, Fuentes R, et al. (2012) Fibrin Generation in Heparin-Induced Thrombocytopenia (HIT): Pathomechanistic Background for Novel Therapy and Prophylaxis Blood. 120: 635-635 |
| Wang Y, Hayes VM, Lu L, et al. (2012) Aryl Hydrocarbon Receptor (AhR) Antagonist Stemregenin 1 (SR1) Enhances in Vitro- and in Vivo-Derived Platelets (PLTs) From Human Megakaryocytes (MKs) Blood. 120: 3450-3450 |
| Fuentes R, Ahn HS, Hayes VM, et al. (2012) Platelet-Targeted, Thrombin-Activatable Fibrinolytic Pro-Drugs As Novel Therapies: Application to the Prothrombotic Disorder of Heparin-Induced Thrombocytopenia (HIT) Blood. 120: 1171-1171 |
| Wang Y, Meng R, Hayes V, et al. (2011) Pleiotropic platelet defects in mice with disrupted FOG1-NuRD interaction. Blood. 118: 6183-91 |