Xiaohui Wang

Affiliations: 
University of Colorado, Boulder, Boulder, CO, United States 
Area:
opioid, pain, TLRs, neuroinflammation, transmembrane protein
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"Xiaohui Wang"
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Publications

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Gao J, Lin C, Zhang C, et al. (2024) Exploring the Function of (+)-Naltrexone Precursors: Their Activity as TLR4 Antagonists and Potential in Treating Morphine Addiction. Journal of Medicinal Chemistry
Kornilov FD, Shabalkina AV, Lin C, et al. (2023) The architecture of transmembrane and cytoplasmic juxtamembrane regions of Toll-like receptors. Nature Communications. 14: 1503
Wang X, Lin C, Wu S, et al. (2022) Cannabidivarin alleviates neuroinflammation by targeting TLR4 co-receptor MD2 and improves morphine-mediated analgesia. Frontiers in Immunology. 13: 929222
Zhang T, Lin C, Wu S, et al. (2022) ACT001 Inhibits TLR4 Signaling by Targeting Co-Receptor MD2 and Attenuates Neuropathic Pain. Frontiers in Immunology. 13: 873054
Wu S, Lin C, Zhang T, et al. (2022) Pentamidine Alleviates Inflammation and Lipopolysaccharide-Induced Sepsis by Inhibiting TLR4 Activation Targeting MD2. Frontiers in Pharmacology. 13: 835081
Kot EF, Wang Y, Goncharuk SA, et al. (2020) Oligomerization analysis as a tool to elucidate the mechanism of EBV latent membrane protein 1 inhibition by pentamidine. Biochimica Et Biophysica Acta. Biomembranes. 183380
Wang Y, Zhang S, Li H, et al. (2020) Small-Molecule Modulators of Toll-like Receptors. Accounts of Chemical Research
Zhang X, Wang Y, Wang H, et al. (2020) Exploring methamphetamine non-enantioselectively targeting Toll-like receptor 4/myeloid differentiation protein 2 by in silico simulations and wet-lab techniques. Journal of Chemical Information and Modeling
Peng Y, Zhang X, Zhang T, et al. (2019) Lovastatin inhibits Toll-like receptor 4 signaling in microglia by targeting its co-receptor myeloid differentiation protein 2 and attenuates neuropathic pain. Brain, Behavior, and Immunity
Wang X, Northcutt AL, Cochran TA, et al. (2019) Methamphetamine activates Toll-like receptor 4 to induce central immune signaling within the ventral tegmental area and contributes to extracellular dopamine increase in the nucleus accumbens shell. Acs Chemical Neuroscience
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