Tobin R. Sosnick
Affiliations: | University of Chicago, Chicago, IL |
Area:
studies of protein and RNA folding, function and designWebsite:
http://sosnick.uchicago.edu/people/trsosnick.htmlGoogle:
"Tobin Sosnick"Bio:
Tobin R. Sosnick was born in 1961 in Woodland, CA. He received his B.A. degree in Physics from The University of California, San Diego, and his Ph.D. degree in Applied Physics studying momentum distributions in superfluid helium in 1989 from Harvard University working under the supervision of Paul Sokol. He was a postdoctoral research fellow with Jill Trewhella and Cliff Unkefer at Los Alamos National Lab (1988-92) and with S. Walter Englander at The University of Pennsylvania (1992-5). After a year as a research assistant professor at UPENN he joined the faculty at the University of Chicago in 1996.
Parents
Sign in to add mentor| Paul E. Sokol | grad student | 1989 | Harvard (Physics Tree) |
| Jill Trewhella | post-doc | 1988-1992 | LANL |
| S. Walter Englander | research scientist | 1992-1995 | Penn |
Children
Sign in to add trainee| Glen M Hocky | research assistant | 2006-2009 | Chicago |
| Tae Yeon Yoo | research assistant | 2009-2011 | Chicago (Cell Biology Tree) |
| Alex Kentsis | grad student | 1994-1998 | Chicago |
| Bryan A. Krantz | grad student | 2002 | Chicago |
| William K. Meisner | grad student | 2004 | Chicago |
| Adarsh D. Pandit | grad student | 2005 | Chicago |
| Gerra L. Bosco | grad student | 2006 | Chicago |
| Nathan J. Baird | grad student | 2007 | Chicago |
| Ali T. Shandiz | grad student | 2007 | Chicago |
| Michael C. Baxa | grad student | 2009 | Chicago |
| Lloyd D. Strickland | grad student | 2009 | Chicago |
| Joseph DeBartolo | grad student | 2010 | Chicago |
| Zhongzhou Zheng | grad student | 2010 | Chicago |
| Aashish N. Adhikari | grad student | 2012 | Chicago |
| Josiah P. Zayner | grad student | 2013 | Chicago |
| George A. Perdrizet | grad student | 2014 | Chicago |
| Alexander French | grad student | 2016 | Chicago (Neurotree) |
| John M. Jumper | grad student | 2011-2017 | Chicago |
| Joshua A. Riback | grad student | 2018 | Chicago |
| Kevin C. Song | grad student | 2012-2019 | Chicago |
| Zongan WANG | grad student | 2014-2020 | Chicago |
| Nabil Faruk | grad student | 2021 | Chicago |
| Adam Zmyslowski | grad student | 2013-2021 | Chicago |
| Ruofan Chen | grad student | 2022 | Chicago |
| Haipeng Gong | post-doc | 2007-2009 | Chicago |
| Wookyung Yu | post-doc | 2012-2016 | Chicago |
| Xiangda Peng | post-doc | 2021 | Chicago |
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Publications
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| Sosnick TR, Baxa MC. (2024) Collapse and Protein Folding: Should We Be Surprised that Biothermodynamics Works So Well? Annual Review of Biophysics |
| Zhang N, Sood D, Guo SC, et al. (2024) Temperature-dependent fold-switching mechanism of the circadian clock protein KaiB. Proceedings of the National Academy of Sciences of the United States of America. 121: e2412327121 |
| Kentsis A, Sosnick TR. (2024) Correction to "Trifluoroethanol Promotes Helix Formation by Destabilizing Backbone Exposure: Desolvation Rather than Native Hydrogen Bonding Defines the Kinetic Pathway of Dimeric Coiled Coil Folding". Biochemistry. 63: 2233 |
| Zhang N, Sood D, Guo SC, et al. (2024) Temperature-Dependent Fold-Switching Mechanism of the Circadian Clock Protein KaiB. Biorxiv : the Preprint Server For Biology |
| Glauninger H, Bard JAM, Wong Hickernell CJ, et al. (2024) Transcriptome-wide mRNA condensation precedes stress granule formation and excludes stress-induced transcripts. Biorxiv : the Preprint Server For Biology |
| Baxa MC, Lin X, Mukinay CD, et al. (2024) How hydrophobicity, side chains, and salt affect the dimensions of disordered proteins. Protein Science : a Publication of the Protein Society. 33: e4986 |
| Keyport Kik S, Christopher D, Glauninger H, et al. (2024) An adaptive biomolecular condensation response is conserved across environmentally divergent species. Nature Communications. 15: 3127 |
| Chen R, Glauninger H, Kahan DN, et al. (2024) HDX-MS finds that partial unfolding with sequential domain activation controls condensation of a cellular stress marker. Proceedings of the National Academy of Sciences of the United States of America. 121: e2321606121 |
| Lin X, Haller PR, Bavi N, et al. (2023) Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility. Elife. 12 |
| Sosnick TR. (2023) AlphaFold developers Demis Hassabis and John Jumper share the 2023 Albert Lasker Basic Medical Research Award. The Journal of Clinical Investigation. 133 |