Martin Egli
Affiliations: | Vanderbilt University, Nashville, TN |
Area:
Biochemistry, GeneticsGoogle:
"Martin Egli"Parents
Sign in to add mentor| Jack David Dunitz | grad student | 1984-1988 | ETH Zürich |
| Vladimir Prelog | grad student | 1984-1988 | ETH Zürich |
| Alexander Rich | post-doc | 1989-1992 | MIT |
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Publications
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| Tomar R, Ghodke PP, Patra A, et al. (2024) DNA Replication across α-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase η. Biochemistry |
| Pallan PS, Lybrand TP, Rozners E, et al. (2023) Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry. Biochemistry |
| Matsuda S, Bala S, Liao JY, et al. (2023) Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs. Journal of the American Chemical Society |
| Richie-Jannetta R, Pallan P, Kingsley PJ, et al. (2023) The peroxidation-derived DNA adduct, 6-oxo-MdG, is a strong block to replication by human DNA polymerase η. The Journal of Biological Chemistry. 105067 |
| Ghosh A, Akabane-Nakata M, Kundu J, et al. (2023) Synthesis and Biophysical Properties of Phosphorodiamidate Piperidino Oligomers. Organic Letters |
| Egli M, Schlegel MK, Manoharan M. (2023) Acyclic (S)-Glycol Nucleic Acid (S-GNA) Modification of siRNAs Improves the Safety of RNAi Therapeutics While Maintaining Potency. Rna (New York, N.Y.) |
| Kellum AH, Pallan PS, Nilforoushan A, et al. (2022) Conformation and Pairing Properties of an -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA. Chemical Research in Toxicology |
| Harp JM, Lybrand TP, Pallan PS, et al. (2022) Cryo neutron crystallography demonstrates influence of RNA 2'-OH orientation on conformation, sugar pucker and water structure. Nucleic Acids Research. 50: 7721-7738 |
| Egli M, Zhang S. (2022) Ned Seeman and the prediction of amino acid-basepair motifs mediating protein-nucleic acid recognition. Biophysical Journal |
| Pallan PS, Lybrand TP, Schlegel MK, et al. (2020) Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost. Biochemistry |