Brooke M. Emerling, Ph.D.
Affiliations: | 2007 | Northwestern University, Evanston, IL |
Area:
Molecular Biology, Cell BiologyGoogle:
"Brooke Emerling"Parents
Sign in to add mentor| Navdeep S. Chandel | grad student | 2007 | Northwestern | |
| (Signaling pathways regulating HIF-1.) | ||||
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Publications
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| Palamiuc L, Johnson JL, Haratipour Z, et al. (2024) Hippo and PI5P4K signaling intersect to control the transcriptional activation of YAP. Science Signaling. 17: eado6266 |
| Yapindi L, Bowley T, Kurtaneck N, et al. (2023) Activation of p53-regulated pro-survival signals and hypoxia-independent mitochondrial targeting of TIGAR by human papillomavirus E6 oncoproteins. Virology. 585: 1-20 |
| Sumita K, Lo YH, Takeuchi K, et al. (2016) The Lipid Kinase PI5P4Kβ Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis. Molecular Cell. 61: 187-98 |
| Emerling BM, Benes CH, Poulogiannis G, et al. (2013) Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients. Proceedings of the National Academy of Sciences of the United States of America. 110: 3483-8 |
| Bell EL, Emerling BM, Ricoult SJ, et al. (2011) SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production. Oncogene. 30: 2986-96 |
| Emerling BM, Weinberg F, Snyder C, et al. (2009) Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio. Free Radical Biology & Medicine. 46: 1386-91 |
| Emerling BM, Weinberg F, Liu JL, et al. (2008) PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a). Proceedings of the National Academy of Sciences of the United States of America. 105: 2622-7 |
| Emerling BM, Viollet B, Tormos KV, et al. (2007) Compound C inhibits hypoxic activation of HIF-1 independent of AMPK. Febs Letters. 581: 5727-31 |
| Bell EL, Emerling BM, Chandel NS. (2005) Mitochondrial regulation of oxygen sensing. Mitochondrion. 5: 322-32 |
| Emerling BM, Chandel NS. (2005) Oxygen sensing: getting pumped by sterols. Science's Stke : Signal Transduction Knowledge Environment. 2005: pe30 |