William M. Wuest, Ph.D.

Affiliations: 
2011-2017 Chemistry Temple University, Philadelphia, PA, United States 
 2017- Chemistry Emory University, Atlanta, GA 
Area:
Bioorganic Chemistry
Website:
https://scholarblogs.emory.edu/wuestlab/
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"William Wuest"
Bio:

B.S. - Paul Helquist - Notre Dame
Ph.D. - Amos B. Smith, III - PENN
Postdoc - Christopher T. Walsh - Harvard Medical School
http://proquest.umi.com/pqdlink?did=1605088061&Fmt=7&clientI d=79356&RQT=309&VName=PQD

Parents

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Paul M. Helquist research assistant 2001-2003 Notre Dame
 (Undergraduate in lab)
Amos B. Smith, III grad student 2008 Penn
 (Progress toward the total synthesis of (+)-peloruside A.)
Christopher T. Walsh post-doc 2008-2011 Harvard Medical School
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Publications

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Smith JR, LeBlanc AR, Wuest WM. (2025) From Natural Products to Small Molecules: Recent Advancements in Anti-MRSA Therapeutics. Acs Medicinal Chemistry Letters. 16: 542-551
Golden MM, Brzezinski CU, Wuest WM. (2025) Target-Guided Design and Synthesis of Aryl-Functionalized Promysalin Analogs. Chembiochem : a European Journal of Chemical Biology. e2401030
Asante JYD, Casey CM, Bezold EL, et al. (2025) Resorcinol-based Bolaamphiphilic Quaternary Ammonium Compounds. Chemmedchem. e202400932
McDonough D, Sanchez CA, Wuest WM, et al. (2025) Recent developments in antimicrobial small molecule quaternary phosphonium compounds (QPCs) - synthesis and biological insights. Rsc Medicinal Chemistry
Rachii D, Bezold EL, Wuest WM, et al. (2024) Bushy-Tailed Multicationic Quaternary Phosphonium Compounds: Potent Amphiphilic Disinfectants with Promising Therapeutic Indices. Chemmedchem. e202400546
Vargas-Cuebas GG, Sanchez CA, Bezold EL, et al. (2024) Adaptations to cationic biocide exposure differentially influence virulence factors and pathogenicity in . Virulence. 15: 2397503
Scharnow AM, Solinski AE, Rowe S, et al. (2024) In Situ Biofilm Affinity-Based Protein Profiling Identifies the Streptococcal Hydrolase GbpB as the Target of a Carolacton-Inspired Chemical Probe. Journal of the American Chemical Society. 146: 23449-23456
Vargas-Cuebas G, Sanchez C, Brayton S, et al. (2024) Exploring the correlation of dynamic surface tension with antimicrobial activities of quaternary ammonium-based disinfectants. Chemmedchem. e202400262
Leatherbury MS, Thierer L, Sanchez CA, et al. (2024) Chimeric Amphiphilic Disinfectants: Quaternary Ammonium / Quaternary Phosphonium Hybrid Structures. Chemmedchem. e202300718
André C, Schrank CL, Cheng Jaramillo AV, et al. (2023) Antimicrobial activity of a new class of synthetic retinoid antibiotics and comparator agents against ocular staphylococci. Frontiers in Antibiotics. 2: 1101450
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