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Douglas A. Melton

Affiliations:

Harvard University, Cambridge, MA, United States

Area:

Development

Website:

http://www.hsci.harvard.edu/node/723

Google:

"Douglas Melton"

Bio:

http://www.scrb.harvard.edu/lab/50/home

Cross-listing: Neurotree - DevTree

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Parents

John B. Gurdon

grad student

University of Cambridge, UK (Neurotree)

Children

Martha R.C. Bhattacharya	research assistant	1996-2000	Harvard (Neurotree)
Lief E Fenno	research assistant	2005-2007	Harvard (Neurotree)
Kyle Loh	research assistant	2008-2008	Harvard (Neurotree)
Miguel R. Santos	grad student	2002	Harvard (Neurotree)
Maya E. Kumar	grad student	2003	Harvard (Neurotree)
Juliana R. Brown	grad student	2005	Harvard (Neurotree)
William J. Anderson	grad student	2000-2006	(DevTree)
Kristen J. Brennand	grad student	2002-2007	Harvard (Neurotree)
Richard I. Sherwood	grad student	2009	Harvard (Neurotree)
Adriana Tajonar	grad student	2012	Harvard (Neurotree)
Sinisa Hrvatin	grad student	2013	Harvard (Neurotree)
Danny Ben-Zvi	post-doc		Harvard
Barak Blum	post-doc		Harvard (DevTree)
Chad Cowan	post-doc		(Cell Biology Tree)
Yuval Dor	post-doc		Harvard (DevTree)
Amy L. Greenwood	post-doc		Harvard (Neurotree)
Matthias Hebrok	post-doc		Harvard (DevTree)
Chris Kintner	post-doc		Harvard Medical School (Neurotree)
Paul A. Krieg	post-doc		Harvard Medical School (Cell Biology Tree)
Kimberly L. Mowry	post-doc		Harvard
XiaoXi Qiao	post-doc		Harvard (Neurotree)
Jayaraj Rajagopal	post-doc		Harvard Medical School (Microtree)
Clifford J. Tabin	post-doc		Harvard
Gerald H. Thomsen	post-doc		Harvard (DevTree)
Daniel L. Weeks	post-doc		Harvard (Neurotree)
Qiao Zhou	post-doc		Harvard (Neurotree)
Peng Yi	post-doc	2008-	Harvard (DevTree)
David Tannahill	post-doc	1987-1989	Harvard
Peter Vize	post-doc	1990-1992	Harvard (DevTree)
Ali Brivanlou	post-doc	1991-1994	Harvard (Neurotree)
Danwei Huangfu	post-doc	2005-2010	Harvard (DevTree)
Rene Maehr	post-doc	2005-2011	Harvard College
Quinn P. Peterson	post-doc	2011-2016	Harvard
Kevin C. Eggan	research scientist	2003-2004	Harvard (Neurotree)

Collaborators

BETA: Related publications

Publications

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Wang X, Brielle S, Kenty-Ryu J, et al. (2025) Improving cellular fitness of human stem cell-derived islets under hypoxia. Nature Communications. 16: 4787
Davis JC, Ryaboshapkina M, Kenty JH, et al. (2024) IAPP Marks Mono-hormonal Stem-cell Derived β Cells that Maintain Stable Insulin Production and . Biorxiv : the Preprint Server For Biology
Magenheim J, Maestro MA, Sharon N, et al. (2023) Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors. Cell Stem Cell. 30: 488-497.e3
Leite NC, Pelayo GC, Melton DA. (2022) Genetic manipulation of stress pathways can protect stem-cell-derived islets from apoptosis in vitro. Stem Cell Reports. 17: 766-774
Gerace D, Kenty JH, Melton DA. (2021) 209.2: Engineering Immune-evasive Human Stem Cell-derived Islet Cells. Transplantation. 105: S13
Sintov E, Gerace D, Melton DA. (2021) A human ESC line for efficient CRISPR editing of pluripotent stem cells. Stem Cell Research. 57: 102591
Gerace D, Boulanger KR, Hyoje-Ryu Kenty J, et al. (2021) Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny. Stem Cell Research. 53: 102371
Cai EP, Ishikawa Y, Zhang W, et al. (2020) Genome-scale in vivo CRISPR screen identifies RNLS as a target for beta cell protection in type 1 diabetes. Nature Metabolism
Leite NC, Sintov E, Meissner TB, et al. (2020) Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells. Cell Reports. 32: 107894
Rasouli N, Melton DA, Alvarez-Dominguez JR. (2020) Purification of Live Stem-Cell-Derived Islet Lineage Intermediates. Current Protocols in Stem Cell Biology. 53: e111