Keith Gagnon

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2010-2015 Chemistry Univ. Southern Illinois 
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"Keith Gagnon"
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Parasrampuria MA, White AA, Chilamkurthy R, et al. (2024) Sequencing-guided design of genetically encoded small RNAs targeting CAG repeats for selective inhibition of mutant . Molecular Therapy. Nucleic Acids. 35: 102206
Sudhakar S, Barkau CL, Chilamkurthy R, et al. (2023) Binding to the Conserved and Stably Folded Guide RNA Pseudoknot Induces Cas12a Conformational Changes During Ribonucleoprotein Assembly. The Journal of Biological Chemistry. 104700
Ageely EA, Chilamkurthy R, Jana S, et al. (2021) Gene editing with CRISPR-Cas12a guides possessing ribose-modified pseudoknot handles. Nature Communications. 12: 6591
Kartje ZJ, Janis HI, Mukhopadhyay S, et al. (2020) Revisiting T7 RNA polymerase transcription in vitro with the Broccoli RNA aptamer as a simplified real-time fluorescent reporter. The Journal of Biological Chemistry
Price DA, Kartje ZJ, Hughes JA, et al. (2020) Infrared Spectroscopy Reveals the Preferred Motif Size and Local Disorder in Parallel Stranded DNA G-quadruplexes. Chembiochem : a European Journal of Chemical Biology
Habibian M, Harikrishna S, Fakhoury J, et al. (2020) Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference. Nucleic Acids Research
Barkau CL, O'Reilly D, Rohilla KJ, et al. (2019) Rationally Designed Small Nucleic Acid-Based Inhibitors of CRISPR-Cas9. Nucleic Acid Therapeutics
Gagnon KT, Corey DR. (2019) Guidelines for Experiments Using Antisense Oligonucleotides and Double-Stranded RNAs. Nucleic Acid Therapeutics
O'Reilly D, Kartje ZJ, Ageely EA, et al. (2018) Extensive CRISPR RNA modification reveals chemical compatibility and structure-activity relationships for Cas9 biochemical activity. Nucleic Acids Research
Kartje ZJ, Barkau CL, Rohilla KJ, et al. (2018) Chimeric Guides Probe and Enhance Cas9 Biochemical Activity. Biochemistry
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