Gary L. Johnson, Ph.D.

Affiliations: 
Pharmacology University of Colorado, Boulder, Boulder, CO, United States 
Website:
http://www.med.unc.edu/pharm/people/primaryfaculty/gary-l-johnson
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"Gary Johnson"
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Publications

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Matkar S, East MP, Stuhlmiller TJ, et al. (2025) Kinome reprogramming of G2/M kinases and repression of MYCN contribute to superior efficacy of lorlatinib in ALK-driven neuroblastoma. Molecular Cancer Therapeutics
East MP, Sprung RW, Okumu DO, et al. (2024) Quantitative proteomic mass spectrometry of protein kinases to determine dynamic heterogeneity of the human kinome. Biorxiv : the Preprint Server For Biology
Berginski ME, Jenner MR, Joisa CU, et al. (2024) Kinome state is predictive of cell viability in pancreatic cancer tumor and cancer-associated fibroblast cell lines. Peerj. 12: e17797
Asquith CRM, East MP, Laitinen T, et al. (2024) Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships. European Journal of Medicinal Chemistry. 271: 116357
Gomez SM, Drewry DH, Willson TM, et al. (2024) Illuminating function of the understudied druggable kinome. Drug Discovery Today. 103881
Joisa CU, Chen KA, Beville S, et al. (2023) Combined kinome inhibition states are predictive of cancer cell line sensitivity to kinase inhibitor combination therapies. Biorxiv : the Preprint Server For Biology
Asquith CRM, Temme L, East MP, et al. (2022) Identification of 4-anilino-quin(az)oline as a cell active Protein Kinase Novel 3 (PKN3) inhibitor chemotype. Chemmedchem
East MP, Johnson GL. (2021) Adaptive chromatin remodeling and transcriptional changes of the functional kinome in tumor cells in response to targeted kinase inhibition. The Journal of Biological Chemistry. 101525
Pucciarelli D, Angus SP, Huang B, et al. (2020) Nf1 mutant tumors undergo transcriptome and kinome re-modeling after inhibition of either mTOR or MEK. Molecular Cancer Therapeutics
Goulet DR, Foster JP, Zawistowski JS, et al. (2020) Discrete Adaptive Responses to MEK Inhibitor in Subpopulations of Triple-Negative Breast Cancer. Molecular Cancer Research : McR
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