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Timothy M. Lohman

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
DNA helicases, SSB proteins, DNA repair, thermodynamics, kinetics
Website:
http://biochem.wustl.edu/faculty/faculty/timothy-lohman
Google:
"Timothy Lohman"
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Parents

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M Thomas Record grad student 1977 UW Madison
 (The thermodynamics and kinetics of charged ligand-nucleic acid interactions and nucleic acid conformational transitions)
Bruno H. Zimm post-doc 1977-1979 UCSD
John A. Schellman post-doc 1979-1981 University of Oregon

Children

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Leslie B. Overman grad student 1989 Texas A & M
Kinlin Chao grad student 1991 Texas A & M
Gregory Runyon grad student 1991 Texas A & M
David P Mascotti grad student 1986-1992 Washington University
Keith Bjornson grad student 1991-1996 Washington University School of Medicine
Wei Cheng grad student 2002 Washington University
Chang-Tai J. Hsieh grad student 2002 Washington University
Aaron L. Lucius grad student 2003 Washington University
Nasib K. Maluf grad student 2003 Washington University
Chun-Ho J. Wong grad student 2006 Washington University
Eric J. Tomko grad student 2010 Washington University
Colin G. Wu grad student 2010 Washington University
Yerdos Ordabayev grad student 2019 Washington University
Lin Hao grad student 2020 Washington University in St. Louis, School of Medicine
Min Kyung Shinn grad student 2020 Washington University
Nicole Fazio grad student 2022 Washington University in St. Louis, School of Medicine
Alexander G. Kozlov post-doc 1995- Washington University School of Medicine
Binh Nguyen post-doc 2007- Washington University School of Medicine
Kacey Mersch post-doc 2022-
Santanu Datta post-doc 1986 Texas A & M
Wlodek Bujalowski post-doc 1990 Texas A & M
Mohan Amaratunga post-doc 1993 Washington University School of Medicine
Marilyn Ferrari post-doc 1994 Washington University School of Medicine
Keith Moore post-doc 1993-1995 Washington University School of Medicine
Janid Ali post-doc 1999 Washington University School of Medicine
George Gauss post-doc 1999 Washington University School of Medicine
Kathleen Brendza post-doc 2003 Washington University School of Medicine
Christopher J. Fischer post-doc 2004 Washington University School of Medicine
S. Kumaran post-doc 2006 Washington University School of Medicine
Anita Niedziela-Majka post-doc 2007 Washington University School of Medicine
Haifeng Jia post-doc 2011 Washington University School of Medicine
Edwin Antony post-doc 2010-2012 Washington University School of Medicine
Fuqian Xie post-doc 2008-2013 Washington University School of Medicine
Vincent Waldman post-doc 2012-2014 Washington University School of Medicine
Michael Simon post-doc 2011-2016 Washington University School of Medicine
Joshua E. Sokoloski post-doc 2015-2017 Washington University School of Medicine
Sumit Kumar Chaturvedi research scientist 2020- Washington University School of Medicine
Isaac Wong division chief 1995 Washington University School of Medicine (Bronchopulmonary Tree)

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Publications

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Chadda A, Nguyen B, Lohman TM, et al. (2024) Structural Basis for Dimerization and Activation of UvrD-family Helicases. Biorxiv : the Preprint Server For Biology
Bonde NJ, Kozlov AG, Cox MM, et al. (2024) Molecular insights into the prototypical single-stranded DNA-binding protein from . Critical Reviews in Biochemistry and Molecular Biology. 1-29
Nguyen B, Hsieh J, Fischer CJ, et al. (2024) Subunit Communication within Dimeric SF1 DNA Helicases. Journal of Molecular Biology. 168578
Fazio NT, Mersch KN, Hao L, et al. (2023) E. coli RecB Nuclease Domain Regulates RecBCD Helicase Activity but not Single Stranded DNA Translocase Activity. Journal of Molecular Biology. 436: 168381
Chadda A, Kozlov AG, Nguyen B, et al. (2023) Mycobacterium tuberculosis Ku stimulates multi-round DNA unwinding by UvrD1 monomers. Journal of Molecular Biology. 168367
Fazio N, Mersch KN, Hao L, et al. (2023) RecBCD Nuclease Domain Regulates Helicase Activity but not Single Stranded DNA Translocase Activity. Biorxiv : the Preprint Server For Biology
Ploetz E, Ambrose B, Barth A, et al. (2023) A new twist on PIFE: photoisomerisation-related fluorescence enhancement. Methods and Applications in Fluorescence
Mersch KN, Sokoloski JE, Nguyen B, et al. (2023) "Helicase" Activity promoted through dynamic interactions between a ssDNA translocase and a diffusing SSB protein. Proceedings of the National Academy of Sciences of the United States of America. 120: e2216777120
Ploetz E, Ambrose B, Barth A, et al. (2023) A new twist on PIFE: photoisomerisation-related fluorescence enhancement. Arxiv
Shinn MK, Chaturvedi SK, Kozlov AG, et al. (2023) Allosteric effects of E. coli SSB and RecR proteins on RecO protein binding to DNA. Nucleic Acids Research
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