David A. Spiegel, Ph.D., MD
Affiliations: | 2007- | Chemistry | Yale University, New Haven, CT |
Area:
natural product synthesisWebsite:
http://www.chem.yale.edu/faculty/spiegel.htmlGoogle:
"David A. Spiegel"Bio:
http://www.spiegelgroup.yale.edu/
http://search.proquest.com/docview/305384340
Parents
Sign in to add mentor| John Louis Wood | grad student | 2005 | Yale | |
| (Synthetic approaches to the phomoidride carbocyclic core and applications.) | ||||
| Stuart L. Schreiber | post-doc | 2005-2007 | Harvard | |
Children
Sign in to add trainee| Alexander Chamessian | research assistant | 2010 | Yale |
| Caitlin Sengelaub | research assistant | 2010 | Yale |
| Ee-Lynn Yap | research assistant | 2012 | Yale |
| Andrew X. Zhang | grad student | 2007-2012 | Yale |
| Patrick J. McEnaney | grad student | 2007-2013 | Yale |
| Christopher G. Parker | grad student | 2007-2013 | Yale |
| Eugene F Douglass | grad student | 2014 | Yale |
| Tina Wang | grad student | 2015 | Yale |
| Brett Blakeley | post-doc | Yale | |
| Cristian Draghici | post-doc | Yale | |
| Anthony F. Rullo | post-doc | 2014- | Yale |
| Thi Trinh | post-doc | 2014- | Yale |
| Kung-pern Wang | post-doc | 2014- | Yale |
| Joshua W.C. Maxwell | post-doc | 2024- | Yale |
| Ryan P. Murelli | post-doc | 2007-2010 | Yale |
| Rendy Kartika | post-doc | 2011 | Yale |
| Dianna L. Bartel | research scientist | Yale | |
| Viswanathan Muthusamy | research scientist | 2008- | Yale |
| Takuji Shoda | research scientist | 2012 | Yale |
BETA: Related publications
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Publications
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| Caianiello DF, Zhang M, Ray JD, et al. (2021) Bifunctional small molecules that mediate the degradation of extracellular proteins. Nature Chemical Biology |
| Douglass EF, Spiegel DA. (2021) Comment on a suite of mathematical solutions to describe ternary complex formation and their application to targeted protein degradation by heterobifunctional ligands. The Journal of Biological Chemistry. 296: 100331 |
| Baumann T, Dunkel A, Schmid C, et al. (2020) Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal. Nature Immunology. 21: 555-566 |
| Sabbasani VR, Wang KP, Streeter MD, et al. (2019) One-Step Synthesis of 2,5-Diaminoimidazoles and Total Synthesis of Methylglyoxal-Derived Imidazolium Crosslink (MODIC). Angewandte Chemie (International Ed. in English) |
| Galligan JJ, Wepy JA, Streeter MD, et al. (2018) Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks. Proceedings of the National Academy of Sciences of the United States of America |
| Leung JC, Bedermann AA, Njardarson JT, et al. (2017) Total Synthesis of (±)-Phomoidride D. Angewandte Chemie (International Ed. in English) |
| Chirkin E, Muthusamy V, Mann P, et al. (2017) Neutralization of pathogenic fungi with small-molecule immunotherapeutics. Angewandte Chemie (International Ed. in English) |
| Sankaranarayanan S, Jamshed M, Kumar A, et al. (2017) Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants. International Journal of Molecular Sciences. 18 |
| Vastl J, Wang T, Trinh TB, et al. (2017) Encoded Silicon-Chip-Based Platform for Combinatorial Synthesis and Screening. Acs Combinatorial Science |
| Vastl J, Kartika R, Park K, et al. (2016) Peptidines: glycine-amidine-based oligomers for solution- and solid-phase synthesis. Chemical Science. 7: 3317-3324 |