Amy C. Rosenzweig, Ph.D.
Affiliations: | Molecular Biosciences | Northwestern University, Evanston, IL |
Area:
bionorganic chemistry, protein crystallographyWebsite:
http://www.chemistry.northwestern.edu/faculty/amy-rosenzweig.htmlGoogle:
"Amy Rosenzweig"Bio:
Rosenzweig, Amy Claire Structural studies of the hydroxylase component of methane monooxygenase from methyloccous capsulatus Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1994.
Research Interests: Bioinorganic chemistry and structural biology, biological methane oxidation and nitrification, metal uptake and transport, oxygen activation by metalloenzymes, membrane proteins
B.S.: Amherst College 1988
Ph.D.: Massachusetts Institute of Technology 1994
Cross-listing: Crystallography Tree
Parents
Sign in to add mentor| Stephen James Lippard | grad student | 1988-1994 | MIT | |
| (Structural studies of the hydroxylase component of methane monooxygenase from methyloccous capsulatus.) | ||||
Children
Sign in to add trainee| Richard J. Jodts | grad student | Northwestern | |
| Walter C. Voegtli | grad student | 2002 | Northwestern |
| Raquel L. Lieberman | grad student | 2005 | Northwestern |
| Carnie Abajian | grad student | 2006 | Northwestern |
| Amanda S. Hakemian | grad student | 2008 | Northwestern |
| Uchechi E. Ukaegbu | grad student | 2009 | Northwestern |
| Matt Traverso | grad student | 2010 | Northwestern |
| Sorabh Agarwal | grad student | 2011 | Northwestern |
| Christopher R. Pope | grad student | 2013 | Northwestern |
| Eliza L. Zielazinski | grad student | 2013 | Northwestern |
| Austin J. Rice | grad student | 2014 | Northwestern |
| Grace E. Kenney | grad student | 2010-2018 | Northwestern |
| Matthew O. Ross | grad student | 2014-2019 | Northwestern |
| Amie K. Boal | post-doc | Northwestern | |
| Laura M. K. Dassama | post-doc | ||
| Aaron T. Smith | post-doc | 2012-2016 | Northwestern |
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Publications
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| Manley OM, Rosenzweig AC. (2025) Copper-chelating natural products. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 30: 111-124 |
| Reyes RM, Rosenzweig AC. (2024) Purification and biochemical characterization of methanobactin biosynthetic enzymes. Methods in Enzymology. 702: 171-187 |
| Reyes RM, Rosenzweig AC. (2024) Methanobactins: Structures, Biosynthesis, and Microbial Diversity. Annual Review of Microbiology |
| Manley OM, Shriver TJ, Xu T, et al. (2024) A multi-iron enzyme installs copper-binding oxazolone/thioamide pairs on a nontypeable virulence factor. Proceedings of the National Academy of Sciences of the United States of America. 121: e2408092121 |
| Jodts RJ, Ho MB, Reyes RM, et al. (2024) Initial Steps in Methanobactin Biosynthesis: Substrate Binding by the Mixed-Valent Diiron Enzyme MbnBC. Biochemistry |
| Tucci FJ, Rosenzweig AC. (2024) Direct Methane Oxidation by Copper- and Iron-Dependent Methane Monooxygenases. Chemical Reviews. 124: 1288-1320 |
| Tucci FJ, Jodts RJ, Hoffman BM, et al. (2023) Product analog binding identifies the copper active site of particulate methane monooxygenase. Nature Catalysis. 6: 1194-1204 |
| Manesis AC, Slater JW, Cantave K, et al. (2023) Capturing a -Fe(IV) State in OB3b MbnH. Biochemistry. 62: 1082-1092 |
| Schachner LF, Soye BD, Ro S, et al. (2022) Revving an Engine of Human Metabolism: Activity Enhancement of Triosephosphate Isomerase via Hemi-Phosphorylation. Acs Chemical Biology |
| Park YJ, Jodts RJ, Slater JW, et al. (2022) A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobactin biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123566119 |