Amy Ruth Howell, Ph.D.

Affiliations: 
1994- Chemistry University of Connecticut, Storrs, CT, United States 
Area:
Synthetic methdology, oxetanes, lactones, spiro compounds
Website:
https://chemistry.uconn.edu/person/amy-howell/
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"Amy Howell"

Parents

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Walter T. Smith grad student 1987 University of Kentucky
 (Synthetic approaches to Azanicotine analogues)
Anthony GM Barrett post-doc 1988 Northwestern
Gerald Pattenden post-doc 1989 Nottingham
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Publications

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An J, Intano J, Richard A, et al. (2021) Easily accessible non-aromatic heterocycles with handles: 4-bromo-2,3-dihydrofurans from 1,2-dibromohomoallylic alcohols. Chemical Science. 12: 10347-10353
Saavedra-Avila NA, Keshipeddy S, Guberman-Pfeffer MJ, et al. (2020) Amide-Linked C4″-Saccharide Modification of KRN7000 Provides Potent Stimulation of Human Invariant NKT Cells and Anti-Tumor Immunity in a Humanized Mouse Model. Acs Chemical Biology
Chandra S, Gray J, Kiosses WB, et al. (2018) Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae. Nature Communications. 9: 4279
Chennamadhavuni D, Saavedra-Avila NA, Carreño LJ, et al. (2018) Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chemical Biology. 25: 925
Chennamadhavuni D, Saavedra-Avila NA, Carreño LJ, et al. (2018) Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity. Cell Chemical Biology
Zhang Y, Senanayake C, Lao K, et al. (2018) Modular Dihydrobenzoazaphosphole Ligands for Suzuki–Miyaura Cross-Coupling Synthesis. 50: 4429-4434
Malapit CA, Luvaga IK, Caldwell DR, et al. (2017) Rh-Catalyzed Conjugate Addition of Aryl and Alkenyl Boronic Acids to α-Methylene-β-lactones: Stereoselective Synthesis of trans-3,4-Disubstituted β-Lactones. Organic Letters
Li S, Diego-Limpin PA, Bajrami B, et al. (2017) Scaling Proteome-wide Reactions of Activity-Based Probes. Analytical Chemistry
Malapit CA, Caldwell DR, Luvaga IK, et al. (2017) Rhodium-Catalyzed Addition of Aryl Boronic Acids to 2,2-Disubstituted Malononitriles. Angewandte Chemie (International Ed. in English)
Betts RJ, Perkovic A, Mahapatra S, et al. (2017) Contact sensitizers trigger human CD1-autoreactive T-cell responses. European Journal of Immunology
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