Ettore J Rastelli, Ph.D.
Affiliations: | 2008-2012 | Chemistry | University of Arkansas, Fayetteville, Fayetteville, AR, United States |
2012-2018 | Chemistry | University of Houston, Houston, TX, United States | |
2018- | Chemistry | University of Pittsburgh, Pittsburgh, PA, United States |
Area:
Organic ChemistryGoogle:
"Ettore Rastelli"Parents
Sign in to add mentorNan Zheng | research assistant | 2010-2012 | University of Arkansas |
Don M. Coltart | grad student | 2012-2017 | University of Houston |
Peter Wipf | post-doc | 2018- | University of Pittsburgh |
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Publications
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Lazo JS, Isbell KN, Vasa SA, et al. (2023) Disruption of ovarian cancer STAT3 and p38 signaling with a small molecule inhibitor of PTP4A3 phosphatase. The Journal of Pharmacology and Experimental Therapeutics |
Lazo JS, Sharlow ER, Cornelison R, et al. (2021) Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer. Biomolecules. 11 |
Rastelli EJ, Sannino S, Hart DJ, et al. (2021) Synthesis and evaluation of bifunctional PTP4A3 phosphatase inhibitors activating the ER stress pathway. Bioorganic & Medicinal Chemistry Letters. 46: 128167 |
Czub MP, Boulton AM, Rastelli EJ, et al. (2020) Structure of the complex of an iminopyridinedione PTP4A3 phosphatase inhibitor with human serum albumin. Molecular Pharmacology |
Coltart DM, Uddin N, Knight J, et al. (2019) On the Mechanism of the Asymmetric Aldol Addition of Chiral N-Amino Cyclic Carbamate Hydrazones: Evidence of Non-Curtin-Hammett Behavior. Chemistry (Weinheim An Der Bergstrasse, Germany) |
Lazo JS, Blanco IK, Tasker NR, et al. (2019) Next-Generation Cell-active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase. The Journal of Pharmacology and Experimental Therapeutics |
Tasker NR, Rastelli EJ, Burnett JC, et al. (2019) Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorganic & Medicinal Chemistry Letters |
Ferguson MW, Gerak CAN, Chow CCT, et al. (2019) The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418. Plos One. 14: e0216423 |
Tasker NR, Rastelli EJ, Blanco IK, et al. (2019) In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors. Organic & Biomolecular Chemistry |
Rastelli EJ, Coltart, DM. (2018) Synthesis and biological activity of apratoxin derivatives Tetrahedron. 74: 2269-2290 |