Parents
Sign in to add mentor| David J. Hartshorne | research assistant | |||
| Daniel E. Koshland | grad student | 1995 | UC Berkeley | |
| (Structure-Function Relationships of the Bacterial Aspartate Receptor.) | ||||
| James E. Darnell | post-doc | Rockefeller (Neurotree) | ||
| John Kuriyan | post-doc | |||
Children
Sign in to add trainee| Yu Cao | post-doc | 2011-2013 | Pfizer Global Research and Development (Crystallography Tree) |
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Publications
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| Mandal PK, Ren Z, Chen X, et al. (2013) Structure-Activity Studies of Phosphopeptidomimetic Prodrugs Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 3 (Stat3). International Journal of Peptide Research and Therapeutics. 19: 3-12 |
| Mandal PK, Gao F, Lu Z, et al. (2011) Potent and selective phosphopeptide mimetic prodrugs targeted to the Src homology 2 (SH2) domain of signal transducer and activator of transcription 3. Journal of Medicinal Chemistry. 54: 3549-63 |
| Hazan-Halevy I, Harris D, Liu Z, et al. (2010) STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells. Blood. 115: 2852-63 |
| Huang S, Chang IS, Lin W, et al. (2010) ARHI (DIRAS3), an imprinted tumour suppressor gene, binds to importins and blocks nuclear import of cargo proteins. Bioscience Reports. 30: 159-68 |
| Mandal PK, Liao WS, Gao F, et al. (2010) Abstract 2527: Potent, highly selective peptidomimetic prodrugs targeting the SH2 domain of Stat3 decrease vasculogenic mimicry, invasion, and anchorage independent growth of cancer cells Cancer Research. 70: 2527-2527 |
| Mandal PK, Ren Z, Chen X, et al. (2009) Structure-affinity relationships of glutamine mimics incorporated into phosphopeptides targeted to the SH2 domain of signal transducer and activator of transcription 3. Journal of Medicinal Chemistry. 52: 6126-41 |
| Lu M, Yang J, Ren Z, et al. (2009) Crystal structure of the three tandem FF domains of the transcription elongation regulator CA150. Journal of Molecular Biology. 393: 397-408 |
| McMurray JS, Mandal PK, Liao WS, et al. (2009) Inhibition of Stat3 by cell-permeable peptidomimetic prodrugs targeted to its SH2 domain. Advances in Experimental Medicine and Biology. 611: 545-6 |
| McMurray JS, Ren Z, Mandal PK, et al. (2009) Model of intermolecular interactions between high affinity phosphopeptides and Stat3. Advances in Experimental Medicine and Biology. 611: 543-4 |
| Mandal PK, Limbrick D, Coleman DR, et al. (2009) Conformationally constrained peptidomimetic inhibitors of signal transducer and activator of transcription. 3: Evaluation and molecular modeling. Journal of Medicinal Chemistry. 52: 2429-42 |