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Gary M. Bokoch

Affiliations: 
1983-1984 Pharmacology University of Texas at Dallas, University of Texas Southwestern Medical Center 
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"Gary Bokoch"
Bio:

From: http://www.asbmb.org/asbmbtoday/asbmbtoday_article_print.aspx?id=7346
It reads: "Gary M. Bokoch passed away last January, after a long struggle with kidney and cardiovascular illness. It is a testament to his strength of character and selflessness that he kept his illness largely a secret for years while soldiering on, until he passed away at age 55. Bokoch was a seminal figure in GTPase biology— for his discoveries, for founding meetings that put the young field on the map, for the impact he had on his colleagues and for the many young scientists that will tell stories about both his tangible and intangible support.

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Parents

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Peter W. Reed grad student Vanderbilt
Alfred G. Gilman post-doc 1983-1984 University of Texas at Dallas, University of Texas Southwestern Medical Center
 (As a postdoctoral fellow, he worked with Nobel laureate Alfred Gilman, and purified and characterized the inhibitory component of adenylate cyclase, Gi)

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Publications

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Gianni D, DerMardirossian C, Bokoch GM. (2011) Direct interaction between Tks proteins and the N-terminal proline-rich region (PRR) of NoxA1 mediates Nox1-dependent ROS generation. European Journal of Cell Biology. 90: 164-71
deCathelineau AM, Bokoch GM. (2009) Inactivation of rho GTPases by statins attenuates anthrax lethal toxin activity. Infection and Immunity. 77: 348-59
Kao YY, Gianni D, Bohl B, et al. (2008) Identification of a conserved Rac-binding site on NADPH oxidases supports a direct GTPase regulatory mechanism. The Journal of Biological Chemistry. 283: 12736-46
Knaus UG, Bamberg A, Bokoch GM. (2007) Rac and Rap GTPase activation assays. Methods in Molecular Biology (Clifton, N.J.). 412: 59-67
Kim JS, Diebold BA, Babior BM, et al. (2007) Regulation of Nox1 activity via protein kinase A-mediated phosphorylation of NoxA1 and 14-3-3 binding. The Journal of Biological Chemistry. 282: 34787-800
Zhao T, Nalbant P, Hoshino M, et al. (2007) Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function. Journal of Leukocyte Biology. 81: 1127-36
DerMardirossian CM, Bokoch GM. (2006) Phosphorylation of RhoGDI by p21-activated kinase 1. Methods in Enzymology. 406: 80-90
DerMardirossian C, Bokoch GM. (2005) GDIs: central regulatory molecules in Rho GTPase activation. Trends in Cell Biology. 15: 356-63
Diebold BA, Fowler B, Lu J, et al. (2004) Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species. The Journal of Biological Chemistry. 279: 28136-42
Zenke FT, Krendel M, DerMardirossian C, et al. (2004) p21-activated Kinase 1 Phosphorylates and Regulates 14-3-3 Binding to GEF-H1, a Microtubule-localized Rho Exchange Factor Journal of Biological Chemistry. 279: 18392-18400
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